Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

Primary aldosteronism is the most common single cause of hypertension and is potentially
curable when only one adrenal gland is the culprit. The importance of primary aldosteronism …

Primary aldosteronism (PA) is the most common cause of secondary hypertension and is
associated with increased morbidity and mortality when compared with blood pressure …

Fluorine is a necessary element for human, which is closely related to life activities, such as
metabolism of teeth and bone tissue. A small amount of fluoride ions can promote the …

BACKGROUND: Primary aldosteronism (PA) has been broadly dichotomized into unilateral
and bilateral forms. Adrenal vein sampling (AVS) lateralization indices (LI)≥ 2 to 4 are the …

Abstract Purpose of Review Primary aldosteronism (PA) affects millions of individuals
worldwide. When unrecognized, PA leads to cardiovascular and renal complications via …

Purpose [11C] Metomidate positron emission tomography (PET) is currently used for staging
of adrenocortical carcinoma and for lateralization in primary aldosteronism (PA). Due to the …

Please see the Editorial Comment by Avinash Medsinge discussing this article. Please see
the Author Video associated with this article. Primary hyperaldosteronism (PA) is the most …

The enzyme aldosterone synthase (CYP11B2) is specifically expressed in aldosterone-
producing tissue of the adrenal cortex and is overexpressed in aldosterone-producing …

In 1953, aldosterone, then termed electrocortin, was first isolated and characterized by
James and Sylvia Tait in London. 1 A year later, Jerome Conn described the first case of …