Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings

RK Gupta, CJ Calderwood, A Yavlinsky, M Krutikov… - Nature medicine, 2020 - nature.com
The risk of tuberculosis (TB) is variable among individuals with latent Mycobacterium
tuberculosis infection (LTBI), but validated estimates of personalized risk are lacking. In …

Parametric multistate survival models: flexible modelling allowing transition‐specific distributions with application to estimating clinically useful measures of effect …

MJ Crowther, PC Lambert - Statistics in medicine, 2017 - Wiley Online Library
Multistate models are increasingly being used to model complex disease profiles. By
modelling transitions between disease states, accounting for competing events at each …

A comparison of statistical methods to predict the residual lifetime risk

SC Conner, A Beiser, EJ Benjamin… - European journal of …, 2022 - Springer
Lifetime risk measures the cumulative risk for developing a disease over one's lifespan.
Modeling the lifetime risk must account for left truncation, the competing risk of death, and …

[PDF][PDF] NICE DSU technical support document 21: flexible methods for survival analysis

MJ Rutherford, PC Lambert, MJ Sweeting… - Decision Support Unit …, 2020 - sheffield.ac.uk
Survival analysis modelling approaches are often required to capture the survival functions
seen in clinical trial data and to further extrapolate to estimate lifetime benefits in economic …

[HTML][HTML] Robustness of individual and marginal model-based estimates: A sensitivity analysis of flexible parametric models

E Syriopoulou, SI Mozumder, MJ Rutherford… - Cancer …, 2019 - Elsevier
Background Flexible parametric survival models (FPMs) are commonly used in
epidemiology. These are preferred as a wide range of hazard shapes can be captured using …

Inequalities in treatment among patients with colon and rectal cancer: a multistate survival model using data from England national cancer registry 2012–2016

S Ling, MA Luque Fernandez, M Quaresma… - British Journal of …, 2024 - nature.com
Background Individual and tumour factors only explain part of observed inequalities in
colorectal cancer survival in England. This study aims to investigate inequalities in treatment …

strcs: A command for fitting flexible parametric survival models on the log-hazard scale

H Bower, MJ Crowther, PC Lambert - The Stata Journal, 2016 - journals.sagepub.com
In this article, we describe strcs, a user-written command for fitting flexible parametric
survival models on the log-hazard scale. strcs is an extension of the user-written stgenreg …

Estimating restricted mean survival time and expected life-years lost in the presence of competing risks within flexible parametric survival models

SI Mozumder, MJ Rutherford, PC Lambert - BMC medical research …, 2021 - Springer
Abstract Background Royston-Parmar flexible parametric survival models (FPMs) can be
fitted on either the cause-specific hazards or cumulative incidence scale in the presence of …

Direct likelihood inference on the cause‐specific cumulative incidence function: a flexible parametric regression modelling approach

SI Mozumder, M Rutherford, P Lambert - Statistics in medicine, 2018 - Wiley Online Library
In a competing risks analysis, interest lies in the cause‐specific cumulative incidence
function (CIF) that can be calculated by either (1) transforming on the cause‐specific hazard …

Bayesian frailty modeling of correlated survival data with application to under-five mortality

RM Alotaibi, HR Rezk, C Guure - BMC Public Health, 2020 - Springer
Background There is high rate of under-five mortality in West Africa with little effort made to
study determinants that significantly increase or decrease its risk across the West African …