The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …

Staphylococcus aureus has been an exceptionally successful pathogen, which is still
relevant in modern age-medicine due to its adaptability and tenacity. This bacterium may be …

During cefoxitin-based nasal screening, phenotypically categorized methicillin-resistant
Staphylococcus aureus (MRSA) was isolated and tested negative for the presence of the …

Emergence of drug resistance has created unmet medical need for the development of new
classes of antibiotics. Discovery of new antibacterial agents with new mode of action …

Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) result in significant
morbidity and mortality for patients in both community and health care settings. This is …

Antimicrobial resistance is an imminent threat worldwide. Methicillin-resistant
Staphylococcus aureus (MRSA) is one of the “superbug” family, manifesting resistance …

Broad-spectrum β-lactam antibiotic resistance in Staphylococcus aureus is a global
healthcare burden,. In clinical strains, resistance is largely controlled by BlaR1, a receptor …

The development of antibiotic resistance in Staphylococcus aureus, particularly in methicillin-
resistant S. aureus (MRSA), has become a significant health concern worldwide. The …

The rise of antibiotic resistance and a dwindling antimicrobial pipeline have been
recognized as emerging threats to public health. The ESKAPE pathogens—Enterococcus …

Background Foot infections are a major cause of morbidity in people with diabetes and the
most common cause of diabetes-related hospitalization and lower extremity amputation …