Extended-spectrum β-lactamases (ESBL): challenges and opportunities

A Husna, MM Rahman, ATM Badruzzaman, MH Sikder… - Biomedicines, 2023 - mdpi.com
The rise of antimicrobial resistance, particularly from extended-spectrum β-lactamase
producing Enterobacteriaceae (ESBL-E), poses a significant global health challenge as it …

Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii with Special Reference to Carbapenemases: A Systematic Review

N Gupta, K Angadi, S Jadhav - Infection and Drug Resistance, 2022 - Taylor & Francis
Carbapenemases are β-lactamase enzymes that hydrolyze a variety of β-lactams including
carbapenem and belong to different Ambler classes (A, B, D). These enzymes can be …

Genomic insights into virulence, antimicrobial resistance, and adaptation acumen of Escherichia coli isolated from an urban environment

P Saini, V Bandsode, A Singh, SK Mendem, T Semmler… - Mbio, 2024 - Am Soc Microbiol
Populations of common commensal bacteria such as Escherichia coli undergo genetic
changes by the acquisition of certain virulence and antimicrobial resistance (AMR) encoding …

Oligosaccharides increase the genotoxic effect of colibactin produced by pks+ Escherichia coli strains

M Oliero, A Calvé, G Fragoso, T Cuisiniere, R Hajjar… - BMC cancer, 2021 - Springer
Background Colibactin is a genotoxin that induces DNA double-strand breaks that may lead
to carcinogenesis and is produced by Escherichia coli strains harboring the pks island …

Evaluation of cinnamon extract effects on clbB gene expression and biofilm formation in Escherichia coli strains isolated from colon cancer patients

F Kosari, M Taheri, A Moradi, R Hakimi Alni… - BMC cancer, 2020 - Springer
Background Colon cancer is one of the most common malignancies and the fourth leading
cause of cancer-related mortality in the world. Colibactin, which is synthesized by the pks …

Poultry‐origin extraintestinal Escherichia coli strains carrying the traits associated with urinary tract infection, sepsis, meningitis and avian colibacillosis in India

PR Meena, P Yadav, H Hemlata… - Journal of Applied …, 2021 - academic.oup.com
Abstract Aim In‐depth 'One Health'risk assessment of extraintestinal pathogenic Escherichia
coli (ExPEC) strains carrying the traits of urinary tract infection, sepsis, meningitis and avian …

High Prevalence of blaCTX-M-15 Gene among Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolates Causing Extraintestinal Infections in …

R Mazumder, A Abdullah, D Ahmed, A Hussain - Antibiotics, 2020 - mdpi.com
The emergence of multidrug-resistant (MDR) Escherichia coli (E. coli) clonal lineages with
high virulence potential is alarming. Lack of sufficient data on molecular epidemiology of …

Prevalence and pathologic effects of colibactin and cytotoxic necrotizing factor-1 (Cnf 1) in Escherichia coli: experimental and bioinformatics analyses

RN Morgan, SE Saleh, HA Farrag, MM Aboulwafa - Gut pathogens, 2019 - Springer
Background The colibactin and cytotoxic necrotizing factor 1 (Cnf 1) are toxins with cell cycle
modulating effects that contribute to tumorgenesis and hyperproliferation. This study aimed …

Genomic and Functional Characterization of Poultry Escherichia coli From India Revealed Diverse Extended-Spectrum β-Lactamase-Producing Lineages With …

A Hussain, S Shaik, A Ranjan, A Suresh… - Frontiers in …, 2019 - frontiersin.org
Extended-spectrum β-lactamases (ESBLs) form the most important resistance determinants
prevalent worldwide. Data on ESBL-producing Escherichia coli from poultry and livestock …

Evolutionary Dynamics Based on Comparative Genomics of Pathogenic Escherichia coli Lineages Harboring Polyketide Synthase (pks) Island

A Suresh, S Shaik, R Baddam, A Ranjan, S Qumar… - MBio, 2021 - Am Soc Microbiol
The genotoxin colibactin is a secondary metabolite produced by the polyketide synthase
(pks) island harbored by extraintestinal pathogenic E. coli (ExPEC) and other members of …