Recent research into the pathophysiology and treatment of atopic dermatitis (AD) has shown
notable progress. An increasing number of aspects of the immune system are being …

The outermost epidermal layer of the skin, the stratum corneum, is not simply a barrier that
safeguards skin integrity from external insults and invaders, it is also a delicately integrated …

Palmoplantar skin is structurally and functionally unique, but the transcriptional programs
driving this specialization are unclear. Here, we use bulk and single-cell RNA sequencing of …

Ultrafine particles (UFP) with a diameter of≤ 0.1 μm, are contributors to ambient air pollution
and derived mainly from traffic emissions, yet their health effects remain poorly …

Skin identity is controlled by intrinsic features of the epidermis and dermis and their
interactions. Modifying skin identity has clinical potential, such as the conversion of residual …

Psoriasis is immune-mediated skin disorder affecting thousands of people. Sphingolipids
(SLs) are bioactive molecules present in the epidermis, involved in the following cellular …

Human skin is stably colonized by a distinct microbiota that functions together with
epidermal cells to maintain a protective physical barrier. Staphylococcus, a prominent genus …

Current insights into skin lipids and their roles in cutaneo... : Current Opinion in Clinical
Nutrition & Metabolic Care Current insights into skin lipids and their roles in cutaneous health …

ERAP1, ERAP2, and LNPEP are aminopeptidases implicated in autoimmune
pathophysiology. In this study, we show that ERAP2 is upregulated and ERAP1 is …

Ceramides are a family of lipids constituted by a sphingoid base and a fatty acid. In the skin,
they are mainly present in the stratum corneum where, with cholesterol and free fatty acids …