[HTML][HTML] HIV-associated neurocognitive disorder (HAND) and Alzheimer's disease pathogenesis: future directions for diagnosis and treatment
M Mustafa, D Musselman, D Jayaweera… - International journal of …, 2024 - mdpi.com
HIV-associated neurocognitive disorder (HAND) and Alzheimer's disease (AD) are two
neurocognitive disorders with overlapping clinical presentations and pathophysiology. The …
neurocognitive disorders with overlapping clinical presentations and pathophysiology. The …
The integrated stress response signaling during the persistent HIV infection
Abstract Human immunodeficiency virus-1 (HIV) infection is a chronic disease under
antiretroviral therapy (ART), during which active HIV replication is effectively suppressed …
antiretroviral therapy (ART), during which active HIV replication is effectively suppressed …
Higher cerebrospinal fluid biomarkers of neuronal injury in HIV-associated neurocognitive impairment
We evaluated whether biomarkers of age-related neuronal injury and amyloid metabolism
are associated with neurocognitive impairment (NCI) in people with and without HIV (PWH …
are associated with neurocognitive impairment (NCI) in people with and without HIV (PWH …
Effects of antiretroviral treatment on central and peripheral immune response in mice with EcoHIV infection
Q Xie, MD Namba, LA Buck, K Park, JG Jackson… - Cells, 2024 - mdpi.com
HIV infection is an ongoing global health issue, despite increased access to antiretroviral
therapy (ART). People living with HIV (PLWH) who are virally suppressed through ART still …
therapy (ART). People living with HIV (PLWH) who are virally suppressed through ART still …
[HTML][HTML] Modulation of tenofovir by probenecid: Impact on drug, interleukin-1β, and dopamine concentration in the prefrontal cortex and cerebellum
SNE Shabalala, M Luvuno, MV Mabandla - Neuroscience, 2024 - Elsevier
The blood–brain barrier's limited permeability to tenofovir restricts its ability to clear HIV from
the brain. Probenecid acting as an adjuvant increases tenofovir concentrations in plasma …
the brain. Probenecid acting as an adjuvant increases tenofovir concentrations in plasma …
Frontal lobe microglia, neurodegenerative protein accumulation, and cognitive function in people with HIV
J Murray, G Meloni, EP Cortes, A KimSilva… - Acta Neuropathologica …, 2022 - Springer
Microglia are implicated in Alzheimer's Disease (AD) pathogenesis. In a middle-aged cohort
enriched for neuroinflammation, we asked whether microgliosis was related to neocortical …
enriched for neuroinflammation, we asked whether microgliosis was related to neocortical …
Does duration of HIV infection substitute for age as a risk factor for amyloid deposition?
JC Ipser, JH Vera - AIDS, 2021 - journals.lww.com
Increasing access to more tolerable antiretroviral therapies (ARTs) has vastly extended the
expected lifespan of people with HIV (PWH), with some models predicting that in developed …
expected lifespan of people with HIV (PWH), with some models predicting that in developed …