Glucagon‐like peptide‐1 (GLP‐1) is an incretin hormone mainly secreted from intestinal L
cells in response to nutrient ingestion. GLP‐1 has beneficial effects for glucose homeostasis …

" It is perhaps today, where a certain underevaluation-well, even disrespect-of scientific
research is growing-useful again and again to refer to the fact of how well suited the …

The 2.2 A resolution crystal structure of recombinant human manganese superoxlde
dismutase, a homotetrameric enzyme that protects mitochondria against oxygen-mediated …

Glucagon-like peptide-1 (GLP-1) stimulates insulin secretion and augments β cell mass via
activation of β cell proliferation and islet neogenesis. We examined whether GLP-1 receptor …

OBJECTIVE To gather preliminary data on the feasibility and efficacy of etanercept therapy
to prolong endogenous insulin production in pediatric patients with newly diagnosed type 1 …

Experimental studies in vitro suggest that cytokines are important mediators in the
pathogenesis of autoimmune insulin-dependent diabetes mellitus (IDDM). However, there is …

Pancreatic β cell plasticity is the primary determinant of disease progression and remission
of type 2 diabetes (T2D). However, the dynamic nature of β cell adaptation remains elusive …

Alginate–poly-l-lysine (PLL) microcapsules can be used for transplantation of insulin-
producing cells for treatment of type I diabetes. In this work we wanted to study the …

Tumor necrosis factor (TNF) alpha is a cytokine that has potent immune regulatory functions.
To assess the potential role of this cytokine in the early development of autoimmunity, we …

Repeated injections of adult mice with recombinant murine TNF prolong the survival of
NZB/W F1 mice, and suppress type I insulin-dependent diabetes mellitus (IDDM) in …