Background Inflammatory licensed mesenchymal stem cells (MSCs) have the ability to
promote functional tissue repair. This study specifically sought to understand how the …

Mesenchymal stem cells (MSCs) have the therapeutic potential to treat a variety of
inflammatory and degenerative disease processes, however the effects of the tissue …

Mesenchymal stromal cells (MSC) have the therapeutic potential to decrease inflammation
due to their immunomodulatory properties. They can be isolated from various tissue sources …

Introduction Equine recurrent uveitis (ERU), an immune mediated disease characterized by
repeated episodes of intra-ocular inflammation, affects 25% of horses in the USA and is the …

Cell therapy has been considered as the third pillar of medicine. There are several kinds of
cells attracted researchers attention whereas the growing interest in mesenchymal stem …

Myocardial infarction (MI) is the most common cause of death in the world. When coronary
artery collapse occurs, myocardial perfusion decreases and the oxygen supply to the heart …

Chronic laminitis is a disabling condition that affects the laminar corium of the horse's
hooves. Commonly, it develops as a collateral injury of numerous primary systemic …

Chronic laminitis is a disabling condition that affects the laminar corium of the horse's
hooves. Commonly, it develops as a collateral injury of numerous primary systemic …

Methods: MSCs were exposed to polyinosinic: polycytidylic acid (poly I: C) to stimulate TLR3
receptors or lipopolysaccharide (LPS) to stimulate TLR4 receptors. MSC phenotype was …

Methods: MSCs were primed with either IFN-γ or poly I: C. Macrophages were isolated and
polarized to an inflammatory phenotype using IFN-γ. Inflammatory licensed MSCs were co …