Nanoparticulate delivery systems have been noticed for chemotherapeutical delivery due to
their ability in controlling the drug release and reducing the side effect. These systems could …

Background Nicotinamide is considered to be effective in halting the Alzheimer's disease
progression. The body could absorb a limited amount of nicotinamide at a time, requiring …

Immune system deficiencies are crucial in the progression of cancer, predominantly
because immune cells are not stimulated by cytokines to eradicate cancer cells …

Solid lipid nanoparticle (SLN) is a promising approach for delivery of various drugs including
proteins and peptides. However, the loading of hydrophilic drugs into the lipoid matrix of …

In this work, we utilize skin penetration enhancers (SPEs) such as ceramide and fatty acids
in lipid nanovesicles to promote the transdermal delivery of active ingredients. These SPE …

To improve the stability and corneal permeability of unstable poorly biocompatible lutein,
lutein solid lipid nanoparticles (Lutein-SLNs) were prepared using ultrasonic assisted …

Neurodegeneration is one of the most common diseases in the aged population,
characterized by the loss in the function of neuronal cells and their ultimate death. One of the …

New biodegradable polymers are needed for use in drug delivery systems to overcome the
high burst release, lack of sustained drug release, and acidic degradation products …

Cocrystallization has emerged as a promising formulation strategy for modulating
transdermal drug absorption by enhancing solubility and permeability. However, challenges …

All-trans retinoic acid (ATRA) has been regarded as a wonder drug for many dermatological
complications; however, its application is limited due to the extreme irritation, and toxicity …