2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS) …

IC Van Gelder, M Rienstra, KV Bunting… - European Heart …, 2024 - academic.oup.com
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

The US Food and Drug Administration Sentinel System: a national resource for a learning health system

JS Brown, AB Mendelsohn, YH Nam… - Journal of the …, 2022 - academic.oup.com
Abstract The US Food and Drug Administration (FDA) created the Sentinel System in
response to a requirement in the FDA Amendments Act of 2007 that the agency establish a …

High-risk medications in persons living with dementia: a randomized clinical trial

S Singh, X Li, NM Cocoros, MT Antonelli… - JAMA Internal …, 2024 - jamanetwork.com
Importance Individuals with Alzheimer disease (AD) and Alzheimer disease–related
dementias (ADRD) may be at increased risk for adverse outcomes relating to inappropriate …

[HTML][HTML] Electronic alerts for ambulatory patients with atrial fibrillation not prescribed anticoagulation: A randomized, controlled trial (AF-ALERT2)

G Piazza, S Hurwitz, U Campia, B Bikdeli, J Lou… - Thrombosis …, 2023 - Elsevier
Background Despite widely available risk stratification tools, safe and effective
anticoagulants, and guideline recommendations, anticoagulation for stroke prevention in …

Pragmatic guidance for embedding pragmatic clinical trials in health plans: Large simple trials aren't so simple

NM Cocoros, JH Gurwitz, MJ Cziraky… - Clinical …, 2023 - journals.sagepub.com
Background: There are unique opportunities related to the design and conduct of pragmatic
trials embedded in health insurance plans, which have longitudinal data on member/patient …

High rates of oral anticoagulation in atrial fibrillation patients observed in a large multi-specialty health system in the Northeast

R Dutta, S Hurley, D Atkins, J Weinstein… - Journal of Interventional …, 2023 - Springer
Background Anticoagulation is a cornerstone in atrial fibrillation (AF) management for stroke
prevention. Studies showed that oral anticoagulants (OAC), previously limited to warfarin …

[HTML][HTML] A targeted educational intervention increases oral anticoagulation rates in high-risk atrial fibrillation patients

R Dutta, JG Ryan, S Hurley, J Wylie - Heart Rhythm O2, 2024 - Elsevier
Background Anticoagulation is the cornerstone of atrial fibrillation (AF) management for
stroke prevention. Recently, we showed that oral anticoagulation (OAC) rates of AF patients …