The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors
CR Weinstein-Oppenheimer, WL Blalock… - Pharmacology & …, 2000 - Elsevier
This review focuses on the Ras–Raf–mitogen-activated protein kinase kinase (MEK)-
extracellular signal-regulated kinase (ERK) signal transduction pathway and the …
extracellular signal-regulated kinase (ERK) signal transduction pathway and the …
Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia
LY Shih, CF Huang, PN Wang, JH Wu, TL Lin, P Dunn… - Leukemia, 2004 - nature.com
The role of internal tandem duplication of fms-like tyrosine kinase 3 (FLT3/ITD), mutations at
tyrosine kinase domain (FLT3/TKD) and N-ras mutations in the transformation of …
tyrosine kinase domain (FLT3/TKD) and N-ras mutations in the transformation of …
Genetic testing in the myelodysplastic syndromes: molecular insights into hematologic diversity
DP Steensma, AF List - Mayo Clinic Proceedings, 2005 - Elsevier
The myelodysplastic syndromes (MDS) are associated with a diverse set of acquired
somatic genetic abnormalities. Bone marrow karyotyping provides important diagnostic and …
somatic genetic abnormalities. Bone marrow karyotyping provides important diagnostic and …
[HTML][HTML] Chronic myelomonocytic leukemia: the role of bone marrow biopsy immunohistology
A Orazi, R Chiu, DP O'Malley, M Czader, SL Allen… - Modern pathology, 2006 - Elsevier
Abstract The World Health Organization criteria for diagnosing chronic myelomonocytic
leukemia (CMML) are largely based on findings observed in the peripheral blood and bone …
leukemia (CMML) are largely based on findings observed in the peripheral blood and bone …
Internal tandem duplication of fms‐like tyrosine kinase 3 is associated with poor outcome in patients with myelodysplastic syndrome
LY Shih, TL Lin, PN Wang, JH Wu, P Dunn, MC Kuo… - Cancer, 2004 - Wiley Online Library
BACKGROUND The prognostic significance of internal tandem duplication (ITD) of the fms‐
like tyrosine kinase 3 gene (FLT3) for patients with myelodysplastic syndrome (MDS) is not …
like tyrosine kinase 3 gene (FLT3) for patients with myelodysplastic syndrome (MDS) is not …
Unbalanced translocation der (1; 7)(q10; p10) defines a unique clinicopathological subgroup of myeloid neoplasms
M Sanada, N Uike, K Ohyashiki, K Ozawa, W Lili… - Leukemia, 2007 - nature.com
Abstract The unbalanced translocation, der (1; 7)(q10; p10), is one of the characteristic
cytogenetic abnormalities found in myelodysplastic syndromes (MDS) and other myeloid …
cytogenetic abnormalities found in myelodysplastic syndromes (MDS) and other myeloid …
The prognostic significance of bone marrow levels of neurofibromatosis‐1 protein and ras oncogene mutations in patients with acute myeloid leukemia and …
D Lu, R Nounou, M Beran, E Estey, T Manshouri… - Cancer, 2003 - Wiley Online Library
BACKGROUND It has been reported that point mutations of the ras gene occur frequently in
acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). However, the …
acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). However, the …
[PDF][PDF] Ποσοτικές μεταβολές των γλυκοπρωτεϊνών της μεμβράνης των αιμοπεταλίων και επίδρασή τους στη λειτουργία αυτών στα μυελοδυσπλαστικά σύνδρομα
Φ Γκιρτοβίτης - 2005 - ikee.lib.auth.gr
Τα Μυελοδυσπλαστικά Σύνδρομα (ΜΔΣ) τα οποία συνιστούν φάσμα παθολογικών
αιματολογικών καταστάσεων αποτελούν στις μέρες μας πεδίο εκτεταμένης επιστημονικής …
αιματολογικών καταστάσεων αποτελούν στις μέρες μας πεδίο εκτεταμένης επιστημονικής …