The extracellular matrix is a network of secreted macromolecules that provides a
harmonious meshwork for the growth and homeostatic development of organisms. It …

Abstract Multimerin-1 (MMRN1) is a platelet protein with a role in haemostasis and
coagulation. It is also present in endothelial cells (ECs) and the extracellular matrix (ECM) …

Background The contribution of the tumor microenvironment and extracellular matrix to the
aggressive biology of Gastric Cancer (GC) has been recently characterized; however, the …

Alterations in extracellular matrix (ECM) components that modulate inflammatory cell
behavior have been shown to serve as early starters for multifactorial diseases such as …

Colon cancer is one of the first tumor types where a functional link between inflammation
and tumor onset has been described; however, the microenvironmental cues affecting colon …

Integrins refer to heterodimers consisting of subunits α and β. They serve as receptors on
cell membranes and interact with extracellular ligands to mediate intracellular molecular …

The extracellular matrix is engaged in an ever-evolving and elegant ballet of dynamic
reciprocity that directly and bi-directionally regulates cell behavior. Homeostatic and …

Collective cell behaviour during embryogenesis and tissue repair requires the coordination
of intercellular junctions, cytoskeleton-dependent shape changes controlled by Rho …

Several studies have demonstrated that melanoma-derived extracellular vesicles (EVs) are
involved in lymph node metastasis; however, the molecular mechanisms involved are not …

The extracellular matrix (ECM) is an important component of the tumor microenvironment
and undergoes extensive remodeling during both initiation and progression of breast cancer …