Roadmap: proton therapy physics and biology

H Paganetti, C Beltran, S Both, L Dong… - Physics in Medicine …, 2021 - iopscience.iop.org
The treatment of cancer with proton radiation therapy was first suggested in 1946 followed
by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated …

Roadmap: helium ion therapy

A Mairani, S Mein, E Blakely, J Debus… - Physics in Medicine …, 2022 - iopscience.iop.org
Helium ion beam therapy for the treatment of cancer was one of several developed and
studied particle treatments in the 1950s, leading to clinical trials beginning in 1975 at the …

Recent advances in radiation therapy and photodynamic therapy

LM Chong, DJH Tng, LLY Tan, MLK Chua… - Applied Physics …, 2021 - pubs.aip.org
In the past 100 years, external beam energy for the treatment of cancer has continually
evolved. Two main modes have been developed. The first is radiotherapy which involves …

Image guidance for FLASH radiotherapy

I El Naqa, BW Pogue, R Zhang, I Oraiqat… - Medical …, 2022 - Wiley Online Library
Abstract FLASH radiotherapy (FLASH‐RT) is an emerging ultra‐high dose (> 40 Gy/s)
delivery that promises to improve the therapeutic potential by limiting toxicities compared to …

Prompt gamma spectroscopy retrieval algorithm for element and density measurements accelerated by cloud computing

JL Wang, XG Wu, ZF Li, SQ Xie, DQ Hei, ZH Zhao… - Frontiers in …, 2022 - frontiersin.org
Prompt gamma ray in proton therapy is the product of a nuclear reaction between a proton
and a target. The characteristic energies and intensities of prompt gamma lines can be used …

[HTML][HTML] Heavy concrete shielding properties for carbon therapy

JL Wang, JJ Lu, DJ Ding, WH Jiang, YD Li… - Nuclear Engineering …, 2023 - Elsevier
As medical facilities are usually built at urban areas, special concrete aggregates and
evaluation methods are needed to optimize the design of concrete walls by balancing …

Investigating the hard X-ray production via proton spallation on different materials to detect elements

S Khezripour, M Rezaie, M Hassanpour… - PloS One, 2023 - journals.plos.org
Various atomic and nuclear methods use hard (high-energy) X-rays to detect elements. The
current study aims to investigate the hard X-ray production rate via high-energy proton beam …

Towards real-time PGS range monitoring in proton therapy of prostate cancer

P Magalhaes Martins, H Freitas, T Tessonnier… - Scientific reports, 2021 - nature.com
Proton therapy of prostate cancer (PCPT) was linked with increased levels of gastrointestinal
toxicity in its early use compared to intensity-modulated radiation therapy (IMRT). The higher …

Non-radioactive elements for prompt gamma enhancement in proton therapy

P Galanakou, T Leventouri, W Muhammad - Radiation Physics and …, 2022 - Elsevier
Abstract Regardless of advanced Prompt Gamma (PG) techniques developed to monitor
proton range in-vivo, poor PG statistics downgrade the potential of their clinical …

A triple-imaging-modality system for simultaneous measurements of prompt gamma photons, prompt x-rays, and induced positrons during proton beam irradiation

S Yamamoto, H Watabe, K Nakanishi… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. Prompt gamma photon, prompt x-ray, and induced positron imaging are possible
methods for observing a proton beam's shape from outside the subject. However, since …