Modular design in natural and biomimetic soft materials
AM Kushner, Z Guan - Angewandte Chemie International …, 2011 - Wiley Online Library
Under eons of evolutionary and environmental pressure, biological systems have developed
strong and lightweight peptide‐based polymeric materials by using the 20 naturally …
strong and lightweight peptide‐based polymeric materials by using the 20 naturally …
Intermediate filament mechanics in vitro and in the cell: from coiled coils to filaments, fibers and networks
Intermediate filament proteins form filaments, fibers and networks both in the cytoplasm and
the nucleus of metazoan cells. Their general structural building plan accommodates highly …
the nucleus of metazoan cells. Their general structural building plan accommodates highly …
When stiffness matters: mechanosensing in heart development and disease
During embryonic morphogenesis, the heart undergoes a complex series of cellular
phenotypic maturations (eg, transition of myocytes from proliferative to quiescent or …
phenotypic maturations (eg, transition of myocytes from proliferative to quiescent or …
End-to-end prediction of multimaterial stress fields and fracture patterns using cycle-consistent adversarial and transformer neural networks
EL Buehler, MJ Buehler - Biomedical Engineering Advances, 2022 - Elsevier
The prediction of stress, strain fields or fracture patterns, along with other physical quantities
as a function of boundary conditions and material microstructure, is an important objective of …
as a function of boundary conditions and material microstructure, is an important objective of …
[HTML][HTML] Physical properties of cytoplasmic intermediate filaments
J Block, V Schroeder, P Pawelzyk… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Intermediate filaments (IFs) constitute a sophisticated filament system in the cytoplasm of
eukaryotes. They form bundles and networks with adapted viscoelastic properties and are …
eukaryotes. They form bundles and networks with adapted viscoelastic properties and are …
Molecular Dynamics Simulation of the -Helix to -Sheet Transition in Coiled Protein Filaments: Evidence for a Critical Filament Length Scale
Z Qin, MJ Buehler - Physical Review Letters, 2010 - APS
The alpha-helix to beta-sheet transition (α-β transition) is a universal deformation
mechanism in alpha-helix rich protein materials such as wool, hair, hoof, and cellular …
mechanism in alpha-helix rich protein materials such as wool, hair, hoof, and cellular …
Nonlinear mechanics of lamin filaments and the meshwork topology build an emergent nuclear lamina
The nuclear lamina—a meshwork of intermediate filaments termed lamins—is primarily
responsible for the mechanical stability of the nucleus in multicellular organisms. However …
responsible for the mechanical stability of the nucleus in multicellular organisms. However …
The cytoskeleton and connected elements in bone cell mechano-transduction
Bone is a mechano-responsive tissue that adapts to changes in its mechanical environment.
Increases in strain lead to increased bone mass acquisition, whereas decreases in strain …
Increases in strain lead to increased bone mass acquisition, whereas decreases in strain …
Molecular interactions driving intermediate filament assembly
PJ Vermeire, G Stalmans, AV Lilina, J Fiala, P Novak… - Cells, 2021 - mdpi.com
Given the role of intermediate filaments (IFs) in normal cell physiology and scores of IF-
linked diseases, the importance of understanding their molecular structure is beyond doubt …
linked diseases, the importance of understanding their molecular structure is beyond doubt …
Opposite responses of normal hepatocytes and hepatocellular carcinoma cells to substrate viscoelasticity
The cellular microenvironment plays a critical role in cell differentiation, proliferation,
migration, and homeostasis. Recent studies have shown the importance of substrate …
migration, and homeostasis. Recent studies have shown the importance of substrate …