Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic

G Ranieri, R Patruno, E Ruggieri… - Current medicinal …, 2006 - ingentaconnect.com
Angiogenesis is important in the growth and progression of solid tumours. The main pro-
angiogenic factor, namely vascular endothelial growth factor (VEGF), also known as …

The safety and efficacy of controlled ovarian hyperstimulation for fertility preservation in women with early breast cancer: a systematic review

RJ Rodgers, GD Reid, J Koch, R Deans… - Human …, 2017 - academic.oup.com
STUDY QUESTION Can controlled ovarian hyperstimulation (COH) for fertility preservation
be effectively conducted in women with breast cancer without worsening their prognosis …

High tumor levels of vascular endothelial growth factor predict poor response to systemic therapy in advanced breast cancer

JA Foekens, HA Peters, N Grebenchtchikov, MP Look… - Cancer research, 2001 - AACR
Vascular endothelial growth factor (VEGF), a potent angiogenic factor, has been reported to
be associated with a poor prognosis in primary breast cancer and in several other cancer …

Identification of functional estrogen response elements in the gene coding for the potent angiogenic factor vascular endothelial growth factor

SM Hyder, Z Nawaz, C Chiappetta, GM Stancel - Cancer Research, 2000 - AACR
Vascular endothelial growth factor (VEGF) is a potent stimulator of angiogenesis and a
prognostic factor for many tumors including those of endocrine-responsive tissues such as …

Phase III trial evaluating the addition of bevacizumab to endocrine therapy as first-line treatment for advanced breast cancer: the letrozole/fulvestrant and avastin (LEA) …

M Martín, S Loibl, G von Minckwitz… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To test whether combining bevacizumab, an anti–vascular endothelial growth
factor treatment, with endocrine therapy (ET) could potentially delay the emergence of …

Vascular endothelial growth factors are differentially regulated by steroid hormones and antiestrogens in breast cancer cells

JK Ruohola, EM Valve, MJ Karkkainen… - Molecular and cellular …, 1999 - Elsevier
Vascular endothelial growth factor (VEGF) is a major inducer of tumor angiogenesis and an
important prognostic factor in breast cancer. Hypoxia is an important inducer of VEGF …

Vascular remodelling during the normal and malignant life cycle of the mammary gland

V Djonov, AC Andres… - Microscopy research and …, 2001 - Wiley Online Library
The mammary gland life cycle is exemplified by massive, physiologically dictated changes in
cell number and composition, architecture, and functionality. These drastic upheavals, by …

Royal jelly has estrogenic effects in vitro and in vivo

S Mishima, KM Suzuki, Y Isohama, N Kuratsu… - Journal of …, 2005 - Elsevier
Royal jelly (RJ) from honeybees (Apis mellifera) is traditionally thought to improve
menopausal symptoms. The potential estrogenic activities of RJ were investigated using …

Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3′-kinase/protein kinase B in prostate …

NJ Mabjeesh, MT Willard, CE Frederickson… - Clinical Cancer …, 2003 - AACR
Purpose: Androgen deprivation is implicated in reducing neoangiogenesis in prostate
cancer (PCA). Androgens regulate the expression of the vascular endothelial growth factor …

Intraoperative radiotherapy for breast cancer

JS Vaidya, JS Tobias, M Baum, M Keshtgar… - The lancet …, 2004 - thelancet.com
Postoperative radiotherapy, which forms part of breastconserving therapy, may not need to
encompass the whole breast. Apart from the consumption of huge resources and patients' …