Alzheimer's disease (AD) is prevalent throughout the world and is the leading cause of
dementia in older individuals (aged≥ 65 years). To gain a deeper understanding of the …

Abstract Alzheimer's disease (AD), the most common neurodegenerative disorder, is
characterized by memory loss and cognitive dysfunction. The accumulation of misfolded …

Introduction Global estimates on numbers of persons in early stages of Alzheimer's disease
(AD), including prodromal and preclinical, are lacking, yet are needed to inform policy …

Importance A National Institute on Aging–Alzheimer's Association (NIA-AA) workgroup
recently published a research framework in which Alzheimer disease is defined by …

Alzheimer's disease (AD) is the most common type of dementia characterized by the
deposition of amyloid beta (Aβ) plaques and tau-neurofibrillary tangles in the brain. Visceral …

Objective To perform a systematic review and meta-analysis to determine whether fluid and
imaging astrocyte biomarkers are altered in Alzheimer disease (AD). Methods PubMed and …

Alzheimer's disease (AD) was used to describe pre-senile dementia to differentiate it from
senile dementia, which develops in the adult age group of more than 65 years. AD is …

Objective To investigate the relationship between the ATN classification system (amyloid,
tau, neurodegeneration) and risk of dementia and cognitive decline in individuals with …

This study investigated differences in retrospective cognitive trajectories between amyloid
and tau PET biomarker stratified groups in initially cognitively unimpaired participants …

Background Alzheimer's disease (AD) pathology begins several years before the clinical
onset. The long preclinical phase is composed of three stages according to the …