Aging is a complex process associated with nearly all diseases. Understanding the
molecular changes underlying aging and identifying therapeutic targets for aging-related …

The auxin-inducible degradation system has been widely adopted in the Caenorhabditis
elegans research community for its ability to empirically control the spatiotemporal …

Accurate transcription is required for the faithful expression of genetic information. However,
relatively little is known about the molecular mechanisms that control the fidelity of …

The actin cytoskeleton is a three‐dimensional scaffold of proteins that is a regulatory,
energyconsuming network with dynamic properties to shape the structure and function of the …

The capacity to deal with stress declines during the aging process, and preservation of
cellular stress responses is critical to healthy aging. The unfolded protein response of the …

Muscle contraction is vital for animal survival, and the sarcomere is the fundamental unit for
this process. However, the functions of many conserved sarcomere proteins remain …

Mitochondria are double membrane-bound organelles with pleiotropic roles in the cell,
including energy production through aerobic respiration, calcium signaling, metabolism …

The auxin-inducible degradation system has been widely adopted in the C. elegans
research community for its ability to empirically control the spatiotemporal expression of …

Targeted protein degradation and genomic profiling at endogenous loci: toolkits development
inspired by C. elegans anchor cell i Page 1 Targeted protein degradation and genomic profiling …

The actin cytoskeleton is a three-dimensional scaffold of proteins that is a regulatory, energy-
consuming network with dynamic properties to shape the structure and function of the cell …