Nanomaterials responsive to endogenous biomarkers for cardiovascular disease theranostics

C Wei, Z Jiang, C Li, P Li, Q Fu - Advanced Functional Materials, 2023 - Wiley Online Library
Cardiovascular disease (CVD) is the number one cause of death worldwide, which propels
the development of advanced technologies for CVD diagnosis and treatment. Biomarker …

Spherical nucleic acids: emerging amplifiers for therapeutic nanoplatforms

Z Tao, H Zhang, S Wu, J Zhang, Y Cheng, L Lei, Y Qin… - Nanoscale, 2024 - pubs.rsc.org
Gene therapy is a revolutionary treatment approach in the 21st century, offering significant
potential for disease prevention and treatment. However, the efficacy of gene delivery is …

Lipophilic NO‐driven nanomotors as drug balloon coating for the treatment of atherosclerosis

X Tang, L Chen, Z Wu, Y Li, J Zeng, W Jiang, W Lv… - Small, 2023 - Wiley Online Library
Drug‐coated balloons (DCB) intervention is an important approach for the treatment of
atherosclerosis (AS). However, this therapeutic approach has the drawbacks of poor drug …

[HTML][HTML] Lifestyle effects on aging and CVD: a spotlight on the nutrient-sensing network

K Yang, R Hou, J Zhao, X Wang, J Wei, X Pan… - Ageing Research …, 2023 - Elsevier
Aging is widespread worldwide and a significant risk factor for cardiovascular disease
(CVD). Mechanisms underlying aging have attracted considerable attention in recent years …

[HTML][HTML] Spherical nucleic acids-based nanoplatforms for tumor precision medicine and immunotherapy

S Liu, CY Yu, H Wei - Materials Today Bio, 2023 - Elsevier
Precise diagnosis and treatment of tumors currently still face considerable challenges due to
the development of highly degreed heterogeneity in the dynamic evolution of tumors. With …

Natural Cell Patches: Melanin Nanoparticles for MR Imaging‐Guided Antiatherosclerosis Therapy via Attenuating Macrophage Pyroptosis

Z Zu, J Sheng, J Qi, Y Miao, Y Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Pyroptosis, characterized by inflammasome activation, membrane Gasdermin D (GSDMD)‐
pore formulation, and the rapid release of inflammatory cytokines, can induce plaque …

Comprehensive view of macrophage autophagy and its application in cardiovascular diseases

W Pan, J Zhang, L Zhang, Y Zhang, Y Song… - Cell …, 2024 - Wiley Online Library
Cardiovascular diseases (CVDs) are the primary drivers of the growing public health
epidemic and the leading cause of premature mortality and economic burden worldwide …

In Vivo Interactions of Nucleic Acid Nanostructures With Cells

Y Xiao, Z Liang, M Shyngys, A Baekova… - Advanced …, 2024 - Wiley Online Library
Nucleic acid nanostructures, derived from the assembly of nucleic acid building blocks (eg,
plasmids and oligonucleotides), are important intracellular carriers of therapeutic cargoes …

Spherical nucleic acids-based biosensors for cancer biomarkers detection

J Li, Y Li, L Pan, W Pan, N Li, B Tang - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Spherical nucleic acids (SNAs) are three-dimensional and polyvalent nanostructures with
highly oriented and densely arranged nucleic acids shell attached to the surface of …

Natural compounds from botanical drugs targeting mTOR signaling pathway as promising therapeutics for atherosclerosis: A review

Q Wu, Q Lv, X Liu, X Ye, L Cao, M Wang, J Li… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis (AS) is a chronic inflammatory disease that is a major cause of
cardiovascular diseases (CVDs), including coronary artery disease, hypertension …