[HTML][HTML] Delirium in critical illness: clinical manifestations, outcomes, and management
Delirium is the most common manifestation of brain dysfunction in critically ill patients. In the
intensive care unit (ICU), duration of delirium is independently predictive of excess death …
intensive care unit (ICU), duration of delirium is independently predictive of excess death …
Tracheostomy in the COVID-19 era: global and multidisciplinary guidance
Global health care is experiencing an unprecedented surge in the number of critically ill
patients who require mechanical ventilation due to the COVID-19 pandemic. The …
patients who require mechanical ventilation due to the COVID-19 pandemic. The …
[HTML][HTML] Oxygen-saturation targets for critically ill adults receiving mechanical ventilation
Background Invasive mechanical ventilation in critically ill adults involves adjusting the
fraction of inspired oxygen to maintain arterial oxygen saturation. The oxygen-saturation …
fraction of inspired oxygen to maintain arterial oxygen saturation. The oxygen-saturation …
Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study
Background To date, 750 000 patients with COVID-19 worldwide have required mechanical
ventilation and thus are at high risk of acute brain dysfunction (coma and delirium). We …
ventilation and thus are at high risk of acute brain dysfunction (coma and delirium). We …
Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 …
The purpose of this document is to highlight practical recommendations to assist acute care
hospitals to prioritize and implement strategies to prevent ventilator-associated pneumonia …
hospitals to prioritize and implement strategies to prevent ventilator-associated pneumonia …
Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study
Background Current management practices and outcomes in weaning from invasive
mechanical ventilation are poorly understood. We aimed to describe the epidemiology …
mechanical ventilation are poorly understood. We aimed to describe the epidemiology …
[HTML][HTML] Analgesia and sedation in patients with ARDS
Abstract Acute Respiratory Distress Syndrome (ARDS) is one of the most demanding
conditions in an Intensive Care Unit (ICU). Management of analgesia and sedation in ARDS …
conditions in an Intensive Care Unit (ICU). Management of analgesia and sedation in ARDS …
[HTML][HTML] Spontaneous-breathing trials with pressure-support ventilation or a T-piece
Background Spontaneous-breathing trials can be performed with the use of either pressure-
support ventilation (PSV) or a T-piece. Whether PSV trials may result in a shorter time to …
support ventilation (PSV) or a T-piece. Whether PSV trials may result in a shorter time to …
Effect of early mobilisation on long-term cognitive impairment in critical illness in the USA: a randomised controlled trial
Background Patients who have received mechanical ventilation can have prolonged
cognitive impairment for which there is no known treatment. We aimed to establish whether …
cognitive impairment for which there is no known treatment. We aimed to establish whether …
Clinical practice guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU
Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management
of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design:
of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design: