New antibiotics for hospital-acquired pneumonia and ventilator-associated pneumonia

M Bassetti, A Mularoni, DR Giacobbe… - … in respiratory and …, 2022 - thieme-connect.com
Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) represent
one of the most common hospital-acquired infections, carrying a significant morbidity and …

Treatment of ventilator-associated pneumonia due to carbapenem-resistant Gram-negative bacteria with novel agents: A contemporary, multidisciplinary ESGCIP …

DR Giacobbe, JA Roberts, MH Abdul-Aziz… - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction In the past 15 years, treatment of ventilator-associated pneumonia (VAP)
caused by carbapenem-resistant Gram-negative bacteria (CR-GNB) has represented an …

Significance of the modified NUTRIC score for predicting clinical outcomes in patients with severe community-acquired pneumonia

CC Tseng, CY Tu, CH Chen, YT Wang, WC Chen… - Nutrients, 2021 - mdpi.com
Nutritional status could affect clinical outcomes in critical patients. We aimed to determine
the prognostic accuracy of the modified Nutrition Risk in Critically Ill (mNUTRIC) score for …

[HTML][HTML] Clinical effectiveness of cefoperazone-sulbactam vs. piperacillin-tazobactam for the treatment of pneumonia in elderly patients

CT Huang, CH Chen, WC Chen, YT Wang… - International Journal of …, 2022 - Elsevier
Objectives Both cefoperazone-sulbactam (CFP-SUL) and piperacillin-tazobactam (PIP-TAZ)
are β-lactam/β-lactamase inhibitor antibiotics and have a similar antimicrobial spectrum …

Novel Siderophore Cephalosporin and Combinations of Cephalosporins with β-Lactamase Inhibitors as an Advancement in Treatment of Ventilator-Associated …

S Viscardi, E Topola, J Sobieraj, A Duda-Madej - Antibiotics, 2024 - mdpi.com
In an era of increasing antibiotic resistance among pathogens, the treatment options for
infectious diseases are diminishing. One of the clinical groups especially vulnerable to this …

The clinical features and risk factors of coagulopathy associated with cefoperazone/sulbactam: a nomogram prediction model

C Xu, J Zhu, K Tu, H Tang, X Zhou, Q Li… - Frontiers in …, 2025 - frontiersin.org
Background Cefoperazone/sulbactam (CPZ/SAM) is an important treatment option for
infections caused by multidrug-resistant gram-negative bacteria. However, it is associated …

[HTML][HTML] Clinical effectiveness of branded versus generic piperacillin-tazobactam for treating severe community-acquired pneumonia

CY Wang, CH Chen, CY Tu, WC Chen, LK Kuo… - Journal of Infection and …, 2022 - Elsevier
Purpose To compare the clinical effectiveness of branded versus generic piperacillin-
tazobactam for treating severe community-acquired pneumonia (CAP). Patients and …

[HTML][HTML] Effects of Tigecycline combined with Cefoperazone on bacterial clearance and serum biochemical indexes in patients with pulmonary infections in ICU

N Li, H Zhang - Pakistan Journal of Medical Sciences, 2022 - ncbi.nlm.nih.gov
Objectives: To investigate the effects of tigecycline combined with Cefoperazone on
bacterial clearance and the expression of serum biochemical indexes [C-reactive protein …

[HTML][HTML] Evaluating the in vitro activity of cefoperazone-sulbactam against Gram negative pathogens in blood stream infections using automated systems

U Qadri, S Zaffar, SJ Wani, S Roohi… - Iranian Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Background and Objectives: The incidence of multidrug-resistant, Gram-negative organisms,
isolated as the etiological agents of infections is ascending. The advent of novel antibiotics …

Clinical Outcomes and Adverse Effects in Septic Patients with Impaired Renal Function Who Received Different Dosages of Cefoperazone–Sulbactam

CH Tai, HJ Tang, CH Lee - Antibiotics, 2022 - mdpi.com
This study aimed to compare clinical outcomes and adverse effects in septic patients with
impaired renal function who received different dosages of cefoperazone–sulbactam (CFP …