BackgroundDespite knowing for many decades that depressive psychopathology is
common in first-episode schizophrenia spectrum disorders (FES), there is limited knowledge …

An increasing amount of research aims at recognizing the molecular mechanisms involved
in long-lasting brain architectural changes induced by antipsychotic treatments. Although …

Genetic mutations in the gene encoding transport protein particle complex 9 (trappc9), a
subunit of TRAPP that acts as a guanine nucleotide exchange factor for rab proteins, cause …

Early‐onset psychosis disorders are serious mental disorders arising before the age of 18
years. Here, we investigate the largest neuroimaging dataset, to date, of patients with early …

Previous structural magnetic resonance imaging studies of psychotic disorders have
demonstrated volumetric alterations in subcortical (ie, the basal ganglia, thalamus) and …

Objective: Pathogenic mutations of the TRAPPC9 gene are the rare genetic causes of
autosomal recessive intellectual disability (ID). There are several features that are not fully …

Prenatal stress is a risk factor for neurodevelopmental disorders (NDDs), including autism
spectrum disorder (ASD). However, how early stress modification of brain development …

Functional dysconnectivity in schizophrenia and affective disorders may be associated with
myelin and oligodendrocyte abnormalities. Altered network integration involving the caudate …

To date, unequivocal neuroanatomical features have been demonstrated neither for
sporadic nor for familial schizophrenia. Here, we investigated the neuroanatomical changes …

Schizophrenia is a severe psychiatric disorder associated with impaired fronto-striatal
functioning. Similar deficits are observed in unaffected siblings of patients, indicating that …