Struma ovarii with atypical features and synchronous primary thyroid cancer: a case report and review of the literature

MR Siegel, RJ Wolsky, EA Alvarez… - Archives of Gynecology …, 2019 - Springer
Purpose To present a case of struma ovarii with a typical features and synchronous primary
thyroid carcinoma and review the available literature to guide diagnosis and management of …

Role of gene sequencing in classifying struma ovarii: BRAF p.G469A mutation and TERT promoter alterations favour malignant struma ovarii

S Neyrand, A Trecourt, J Lopez, PA Just… - …, 2024 - Wiley Online Library
Aims Struma ovarii (SO) are rare, accounting for 0.3–1% of ovarian tumours, and include
benign and malignant lesions. In most cases, histology is not predictive of clinical outcome …

Struma Ovarii Associated with Ascites and elevated CA125: two case reports and review of the literature

S Wang, X He, H Yang, L Chen - International Journal of Women's …, 2022 - Taylor & Francis
Struma ovarii is a rare variety of specialized monodermal mature ovarian teratoma, it is
composed predominantly of thyroid tissue. Ascites is present in one third of patients. The …

Malignant struma ovarii: From case to analysis

S Ayhan, F Kilic, B Ersak, O Aytekin… - Journal of Obstetrics …, 2021 - Wiley Online Library
Aim To evaluate the clinico‐pathologic features, treatment options, prognostic factors, and
survival outcomes of malignant struma ovarii based on a systematic literature review in …

Treatment for malignant struma ovarii in the eyes of thyroid surgeons: a case report and study of Chinese cases reported in the literature

J Luo, C Xie, Z Li - Medicine, 2014 - journals.lww.com
Malignant struma ovarii (MSO) is a rare malignant ovarian germ cell tumor that has been
scarcely reported by thyroid surgeons focusing on treatment. There are no golden standards …

Malignant struma ovarii: next-generation sequencing of six cases revealed Nras, Braf, and Jak3 mutations

R Poli, M Scatolini, E Grosso, F Maletta, M Gallo… - Endocrine, 2021 - Springer
Purpose Struma ovarii (SO) is a highly specialized ovarian teratoma, consisting of thyroid
tissue. Rarely, carcinomas histologically identical to their thyroid counterparts may occur …

Novel BRAF and KRAS Mutations in Papillary Thyroid Carcinoma Arising in Struma Ovarii

A Tan, CJR Stewart, KL Garrett, M Rye, PA Cohen - Endocrine pathology, 2015 - Springer
Papillary carcinomas of thyroid type rarely arise within struma ovarii. There are limited data
on the immunohistochemical and molecular features of these tumors. Three cases of …

The largest reported papillary thyroid carcinoma arising in struma ovarii and metastasis to opposite ovary: case report and review of literature

MS Al Hassan, T Saafan, W El Ansari, AA Al Ansari… - Thyroid Research, 2018 - Springer
Background Malignant struma ovarii (MSO) is a very rare, germ cell tumor of the ovary,
histologically identical to differentiated thyroid cancers. Struma ovarii (SO) is difficult to …

Identifying the Carcinogenic Mechanism of Malignant Struma Ovarii Using Whole-Exome Sequencing and DNA Methylation Analysis

H Yamashita, K Nakayama, K Kanno… - Current Issues in …, 2023 - mdpi.com
Background: Since malignant struma ovarii is a very rare disease, its carcinogenic
mechanism has not been elucidated. Here, we sought to identify the genetic lesions that …

Inactivation of retinoblastoma protein (Rb1) in the oocyte: evidence that dysregulated follicle growth drives ovarian teratoma formation in mice

QE Yang, SI Nagaoka, I Gwost, PA Hunt… - PLoS genetics, 2015 - journals.plos.org
The origin of most ovarian tumors is undefined. Here, we report development of a novel
mouse model in which conditional inactivation of the tumor suppressor gene Rb1 in oocytes …