Protein phosphorylation is one of the most widely observed and important post-translational
modification (PTM) processes. Protein phosphorylation is regulated by protein kinases, each …

The liver enzyme phenylalanine hydroxylase is responsible for conversion of excess
phenylalanine in the diet to tyrosine. Phenylalanine hydroxylase is activated by …

Improved understanding of the relationship among structure, dynamics, and function for the
enzyme phenylalanine hydroxylase (PAH) can lead to needed new therapies for …

The myriads of molecular pathways that have been measured to understand the physical
bases of neuronal and other cellular functions have exceeded classical comprehension. In …

Protein phosphorylation is a post-translational modification that enables various cellular
activities and plays essential roles in protein interactions. Phosphorylation is an important …

Phosphorylation is one of the main regulators of cellular signaling typically occurring in
flexible parts of folded proteins and in intrinsically disordered regions. It can have distinct …

Intrinsically disordered proteins (IDPs) are involved in many pivotal cellular processes
including phosphorylation and signalling. The structural and functional effects of …

The plausible explanation behind the stability of thermophilic protein is still yet to be defined
more clearly. Here, an in silico study has been undertaken by investigating the sequence …

In Chinese hamster ovary cells expressing rabbit sodium‐dependent glucose transporter
(rbSGLT1) protein kinase A (PKA) activators (forskolin and 8‐Br‐cAMP) stimulated α‐methyl …

Publisher Summary Phenylketonuria (PKU) is a disease caused by deleterious mutations in
phenylalanine hydroxylase (PAH) and constitutes a paradigm for misfolding diseases …