Polyphenols constitute an important group of natural products that are traditionally
associated with a wide range of bioactivities. These are usually found in low concentrations …

Frequent p53 mutations (mutp53) not only abolish tumor suppressor capacities but confer
various gain-of-function (GOF) activities that impacts molecules and pathways now regarded …

Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for
prevention and therapy of colorectal cancer/CRC. However, the exact mechanism of action …

Simple Summary Breast cancer remains the most commonly diagnosed cancer and the
leading cause of cancer death among females worldwide. It is a highly heterogeneous …

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality
worldwide, and its abnormal metabolism affects the survival and prognosis of patients …

Scope Some polyphenol‐derived metabolites reach human breast cancer (BC) tissues at
concentrations that induce cell senescence. However, this is unknown for isoflavones …

Cancer arises through a complex interplay between genetic, behavioral, metabolic, and
environmental factors that combined trigger cellular changes that over time promote …

At present, the growing spread of tumor cases worldwide renders the research of new
promising and selective anticancer drugs urgent. The biological action of extracts of …

Background: Diabetes is an increasingly prevalent global disease caused by the impairment
in insulin production or insulin function. Diabetes in the long term causes both microvascular …

The p53 protein, encoded by the TP53 gene, serves as a critical tumor suppressor, playing a
vital role in maintaining genomic stability and regulating cellular responses to stress …