The CytoFLEX is a novel semiconductor-based flow cytometer that utilizes avalanche
photodiodes, wavelength-division multiplexing, enhanced optics, and diode lasers to …

The packaging and budding of Gag polyprotein and viral RNA is a critical step in the HIV-1
life cycle. High-resolution structures of the Gag polyprotein have revealed that the capsid …

Virus families have evolved different strategies for genome uncoating, which are also
followed by recombinant vectors. Vectors derived from adeno-associated viruses (AAV) are …

The limited biomolecular and functional stability of lentiviral vectors (LVVs) for cell therapy
poses the need for analytical tools that can monitor their titers and activity throughout the …

Monitoring virus assembly at the nanoscale in host cells remains a major challenge. Human
immunodeficiency virus type 1 (HIV-1) components are addressed to the plasma membrane …

Circular RNAs (circRNAs) are a class of single-stranded RNAs with a closed loop lacking 5ʹ
and 3ʹ ends. These circRNAs are translatable and, therefore, have a potential in …

The ongoing outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2) started in late 2019 and spread across the world, infecting millions of people, with over …

Virus-like particles (VLPs) have become a promising platform for vaccine production. VLPs
are formed by structural viral proteins that inherently self-assemble when expressed in a …

Screening of unknown particles, including viruses and nanoparticles, is key in medicine,
industry and pollutant determination. However, existing techniques require sample a priori …

The downstream processing of enveloped virus‐like particles is very challenging because of
the biophysical and structural similarity between correctly assembled particles and …