NF-κB pathway as a potential target for treatment of critical stage COVID-19 patients
R Kircheis, E Haasbach, D Lueftenegger… - Frontiers in …, 2020 - frontiersin.org
Patients infected with SARS-CoV-2 show a wide spectrum of clinical manifestations ranging
from mild febrile illness and cough up to acute respiratory distress syndrome, multiple organ …
from mild febrile illness and cough up to acute respiratory distress syndrome, multiple organ …
VDA-RWLRLS: An anti-SARS-CoV-2 drug prioritizing framework combining an unbalanced bi-random walk and Laplacian regularized least squares
L Shen, F Liu, L Huang, G Liu, L Zhou… - Computers in biology and …, 2022 - Elsevier
Background A new coronavirus disease named COVID-19, caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), is rapidly spreading worldwide …
respiratory syndrome coronavirus-2 (SARS-CoV-2), is rapidly spreading worldwide …
Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients
C Loucera, M Peña-Chilet, M Esteban-Medina… - Scientific reports, 2021 - nature.com
COVID-19 is a major worldwide health problem because of acute respiratory distress
syndrome, and mortality. Several lines of evidence have suggested a relationship between …
syndrome, and mortality. Several lines of evidence have suggested a relationship between …
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms
We need to effectively combine the knowledge from surging literature with complex datasets
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
COVID infection in 4 steps: Thermodynamic considerations reveal how viral mucosal diffusion, target receptor affinity and furin cleavage act in concert to drive the …
We have developed a mechanistic model of SARS-CoV-2 and SARS-CoV infection,
exploring the relationship between the viral diffusion in the mucosa and viral affinity for the …
exploring the relationship between the viral diffusion in the mucosa and viral affinity for the …
Real-world evidence with a retrospective cohort of 15,968 COVID-19 hospitalized patients suggests 21 new effective treatments
Purpose Despite the extensive vaccination campaigns in many countries, COVID-19 is still a
major worldwide health problem because of its associated morbidity and mortality …
major worldwide health problem because of its associated morbidity and mortality …
The wind of change: Gibbs energy of binding and infectivity evolution of Omicron BA. 2.86 Pirola, EG. 5.1, XBB. 1.16 Arcturus, CH. 1.1 and BN. 1 variants of SARS-CoV …
ME Popović, G Šekularac, M Popović - Microbial Risk Analysis, 2024 - Elsevier
A question is often asked about what tomorrow brings. During the last 4 years of the COVID-
19 pandemic, this question was asked with every appearance of a new SARS-CoV-2 …
19 pandemic, this question was asked with every appearance of a new SARS-CoV-2 …
CovMulNet19, integrating proteins, diseases, drugs, and symptoms: a network medicine approach to COVID-19
Introduction: We introduce in this study CovMulNet19, a comprehensive COVID-19 network
containing all available known interactions involving SARS-CoV-2 proteins, interacting …
containing all available known interactions involving SARS-CoV-2 proteins, interacting …
Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches
A Niarakis, M Ostaszewski, A Mazein… - Frontiers in …, 2024 - frontiersin.org
Introduction The COVID-19 Disease Map project is a large-scale community effort uniting
277 scientists from 130 Institutions around the globe. We use high-quality, mechanistic …
277 scientists from 130 Institutions around the globe. We use high-quality, mechanistic …
Real-world evidence with a retrospective cohort of 15,968 Andalusian COVID-19 hospitalized patients suggests 21 new effective treatments and one drug that …
Despite the extensive vaccination campaigns in many countries, COVID-19 is still a major
worldwide health problem because of its associated morbidity and mortality. Therefore …
worldwide health problem because of its associated morbidity and mortality. Therefore …