Health benefits of resveratrol: Evidence from clinical studies

AP Singh, R Singh, SS Verma, V Rai… - Medicinal research …, 2019 - Wiley Online Library
Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

Moroccan antidiabetic medicinal plants: Ethnobotanical studies, phytochemical bioactive compounds, preclinical investigations, toxicological validations and clinical …

A Bouyahya, N El Omari, N Elmenyiy… - Trends in Food Science …, 2021 - Elsevier
Background Moroccan flora is rich with medicinal plants that are widely used in traditional
medicine for the treatment of various diseases including diabetes. These plants possess …

Unravelling the mechanisms regulating muscle mitochondrial biogenesis

DA Hood, LD Tryon, HN Carter, Y Kim… - Biochemical …, 2016 - portlandpress.com
Skeletal muscle is a tissue with a low mitochondrial content under basal conditions, but it is
responsive to acute increases in contractile activity patterns (ie exercise) which initiate the …

[HTML][HTML] Resveratrol for the management of human health: how far have we come? A systematic review of resveratrol clinical trials to highlight gaps and opportunities

K Brown, D Theofanous, RG Britton, G Aburido… - International Journal of …, 2024 - mdpi.com
Resveratrol has long been proposed as being beneficial to human health across multiple
morbidities, yet there is currently no conclusive clinical evidence to advocate its …

[HTML][HTML] Resveratrol, a multitasking molecule that improves skeletal muscle health

L Toniolo, M Concato, E Giacomello - Nutrients, 2023 - mdpi.com
Resveratrol is a natural polyphenol utilized in Chinese traditional medicine and thought to
be one of the determinants of the “French Paradox”. More recently, some groups evidenced …

Looking beyond PGC-1α: emerging regulators of exercise-induced skeletal muscle mitochondrial biogenesis and their activation by dietary compounds

H Islam, DA Hood, BJ Gurd - Applied Physiology, Nutrition, and …, 2020 - cdnsciencepub.com
Despite its widespread acceptance as the “master regulator” of mitochondrial biogenesis (ie,
the expansion of the mitochondrial reticulum), peroxisome proliferator-activated receptor …

Resveratrol and lifespan in model organisms

K Pallauf, G Rimbach, PM Rupp… - Current medicinal …, 2016 - ingentaconnect.com
Background: Resveratrol may possess life-prolonging and health-benefitting properties,
some of which may resemble the effect of caloric restriction (CR). CR appears to prolong the …

Adipose tissue NAD+ biology in obesity and insulin resistance: From mechanism to therapy

S Yamaguchi, J Yoshino - Bioessays, 2017 - Wiley Online Library
Nicotinamide adenine dinucleotide (NAD+) biosynthetic pathway, mediated by nicotinamide
phosphoribosyltransferase (NAMPT), a key NAD+ biosynthetic enzyme, plays a pivotal role …

[HTML][HTML] Targeting Sirt1, AMPK, Nrf2, CK2, and soluble guanylate cyclase with nutraceuticals: a practical strategy for preserving bone mass

MF McCarty, L Lewis Lujan, S Iloki Assanga - International Journal of …, 2022 - mdpi.com
There is a vast pre-clinical literature suggesting that certain nutraceuticals have the potential
to aid the preservation of bone mass in the context of estrogen withdrawal, glucocorticoid …

[HTML][HTML] Nutrigenomics in regulating the expression of genes related to type 2 diabetes mellitus

K Felisbino, JG Granzotti, L Bello-Santos… - Frontiers in …, 2021 - frontiersin.org
Nutrigenomics is the study of the gene-nutrient interaction and it indicates that some
nutrients, called bioactive compounds, can mold the genetic expression or change the …