Systemic inflammation in hemorrhagic strokes–A novel neurological sign and therapeutic target?

AR Saand, F Yu, J Chen… - Journal of Cerebral Blood …, 2019 - journals.sagepub.com
Growing evidences suggest that stroke is a systemic disease affecting many organ systems
beyond the brain. Stroke-related systemic inflammatory response and immune …

Deciphering the iron side of stroke: neurodegeneration at the crossroads between iron dyshomeostasis, excitotoxicity, and ferroptosis

N DeGregorio-Rocasolano, O Martí-Sistac… - Frontiers in …, 2019 - frontiersin.org
In general, iron represents a double-edged sword in metabolism in most tissues, especially
in the brain. Although the high metabolic demands of brain cells require iron as a redox …

IL-4/STAT6 signaling facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice

J Xu, Z Chen, F Yu, H Liu, C Ma, D Xie… - Proceedings of the …, 2020 - National Acad Sciences
Intracerebral hemorrhage (ICH) is a devastating form of stroke affecting millions of people
worldwide. Parenchymal hematoma triggers a series of reactions leading to primary and …

Minocycline attenuates brain injury and iron overload after intracerebral hemorrhage in aged female rats

S Dai, Y Hua, RF Keep, N Novakovic, Z Fei, G Xi - Neurobiology of disease, 2019 - Elsevier
Brain iron overload is involved in brain injury after intracerebral hemorrhage (ICH). There is
evidence that systemic administration of minocycline reduces brain iron level and improves …

The chemical basis of intracerebral hemorrhage and cell toxicity with contributions from eryptosis and ferroptosis

PJ Derry, ATT Vo, A Gnanansekaran, J Mitra… - Frontiers in Cellular …, 2020 - frontiersin.org
Intracerebral hemorrhage (ICH) is a particularly devastating event both because of the direct
injury from space-occupying blood to the sequelae of the brain exposed to free blood …

The role and therapeutic potential of heat shock proteins in haemorrhagic stroke

A Shao, Y Zhou, Y Yao, W Zhang… - Journal of Cellular …, 2019 - Wiley Online Library
Heat shock proteins (HSPs) are induced after haemorrhagic stroke, which includes
subarachnoid haemorrhage (SAH) and intracerebral haemorrhage (ICH). Most of these …

A systematic review and meta‐analysis of abnormalities in hematological and biochemical markers among Bangladeshi COVID‐19 cases

KK Bhowmik, MA Barek, MA Aziz… - Health Science …, 2022 - Wiley Online Library
Abstract Background and Aims Abnormalities in hematological and biochemical markers are
assumed to be associated with the progression of COVID‐19 disease. This meta‐analysis …

Macrophage CD163 expression in cerebrospinal fluid: association with subarachnoid hemorrhage outcome

AJ Thomas, CS Ogilvy, CJ Griessenauer… - Journal of …, 2018 - thejns.org
OBJECTIVE Even though heme-induced cerebral inflammation contributes to many of the
adverse sequelae seen in patients with subarachnoid hemorrhage (SAH), little is known …

Acute inflammation in cerebrovascular disease: a critical reappraisal with focus on human studies

RA Dias, L Dias, E Azevedo, P Castro - Life, 2021 - mdpi.com
Recent attention has been focused on the field of inflammatory biomarkers associated with
vascular disorders, regarding diagnosis, prognosis, and possible therapeutical targets. In …

The predictive role of the neutrophil-lymphocyte ratio in the prognosis of adult patients with stroke

J Wan, X Wang, Y Zhen, X Chen, P Yao… - Chinese neurosurgical …, 2020 - mednexus.org
Our study aimed to determine the effect of the neutrophil-lymphocyte ratio on the prognosis
of adult patients with acute stroke. We searched the Web of Science, PubMed, Embase …