[HTML][HTML] MicroRNA: A signature for cancer progression
MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …
control expression of genes by targeting mRNAs. miRNA alterations partake in the …
Tumor suppressor miRNA in cancer cells and the tumor microenvironment: mechanism of deregulation and clinical implications
K Otmani, P Lewalle - Frontiers in oncology, 2021 - frontiersin.org
MicroRNAs (miRNAs) are noncoding RNAs that have been identified as important
posttranscriptional regulators of gene expression. miRNAs production is controlled at …
posttranscriptional regulators of gene expression. miRNAs production is controlled at …
ROR1: an orphan becomes apparent
TJ Kipps - Blood, The Journal of the American Society of …, 2022 - ashpublications.org
Since its initial identification in 1992 as a possible class 1 cell-surface receptor without a
known parent ligand, receptor tyrosine kinase–like orphan receptor 1 (ROR1) has stimulated …
known parent ligand, receptor tyrosine kinase–like orphan receptor 1 (ROR1) has stimulated …
Epigenetic regulation in hematopoiesis and its implications in the targeted therapy of hematologic malignancies
A Zhao, H Zhou, J Yang, M Li, T Niu - Signal Transduction and Targeted …, 2023 - nature.com
Hematologic malignancies are one of the most common cancers, and the incidence has
been rising in recent decades. The clinical and molecular features of hematologic …
been rising in recent decades. The clinical and molecular features of hematologic …
tRNA-derived fragments (tRFs) in cancer
Abstract tRNA fragments (tRNA derived fragments or tRFs) are small single stranded RNA
molecules derived from pre-tRNAs and mature tRNAs. tRFs have been known for a number …
molecules derived from pre-tRNAs and mature tRNAs. tRFs have been known for a number …
High expression level of ROR1 and ROR1-signaling associates with venetoclax resistance in chronic lymphocytic leukemia
Although the BH3-mimetic venetoclax is highly cytotoxic for chronic lymphocytic leukemia
(CLL) cells, some patients with CLL fail to clear minimal residual disease (MRD). We …
(CLL) cells, some patients with CLL fail to clear minimal residual disease (MRD). We …
MicroRNAs: Tiny regulators of gene expression with pivotal roles in normal B-Cell development and B-Cell chronic lymphocytic leukemia
Simple Summary The involvement of miRNAs in physiological cellular processes has been
well documented. The development of B cells, which is dictated by a miRNA-transcription …
well documented. The development of B cells, which is dictated by a miRNA-transcription …
[HTML][HTML] Stage-specific treatment of colorectal cancer: A microRNA-nanocomposite approach
Colorectal cancer (CRC) is among the leading causes of cancer mortality. The lifetime risk of
developing CRC is about 5% in adult males and females. CRC is usually diagnosed at an …
developing CRC is about 5% in adult males and females. CRC is usually diagnosed at an …
Therapeutic advances in the targeting of ROR1 in hematological cancers
Receptor tyrosine kinases (RTKs) are key cell surface receptors involved in cell
communication and signal transduction, with great importance in cell growth, differentiation …
communication and signal transduction, with great importance in cell growth, differentiation …
Molecular mechanisms associated with ROR1-mediated drug resistance: crosstalk with Hippo-YAP/TAZ and BMI-1 pathways
H Karvonen, H Barker, L Kaleva, W Niininen… - Cells, 2019 - mdpi.com
Signaling via the Wnt-related receptor tyrosine kinase-like orphan receptor 1 (ROR1)
triggers tumorigenic features associated with cancer stem cells (CSCs) and epithelial …
triggers tumorigenic features associated with cancer stem cells (CSCs) and epithelial …