In recent years, an abundance of new molecular structures have been elucidated using cryo-
electron microscopy (cryo-EM), largely due to advances in hardware technology and data …

Cryo-electron microscopy (CryoEM) has become a vital technique in structural biology. It is
an interdisciplinary field that takes advantage of advances in biochemistry, physics, and …

Since the beginning of electron microscopy, resolution has been a critical parameter. In this
article, we propose a fully automatic, accurate method for determining the local resolution of …

Cryo-electron microscopy (cryoEM) has become a well established technique to elucidate
the 3D structures of biological macromolecules. Projection images from thousands of …

We propose two new measures of resolution anisotropy for cryogenic electron microscopy
maps: Fourier shell occupancy (FSO), and the Bingham test (BT). FSO varies from 1 to 0 …

In this article, a method is presented to estimate a new local quality measure for 3D cryoEM
maps that adopts the form of alocal resolution'type of information. The algorithm (DeepRes) …

X-ray crystallography and single-particle analysis cryogenic electron microscopy are
essential techniques for uncovering the three-dimensional structures of biological …

In recent years, advances in cryoEM have dramatically increased the resolution of
reconstructions and, with it, the number of solved atomic models. It is widely accepted that …

Xmipp is an open-source software package consisting of multiple programs for processing
data originating from electron microscopy and electron tomography, designed and managed …

Virtually all single-particle cryo-EM experiments currently suffer from specimen adherence to
the air-water interface, leading to a non-uniform distribution in the set of projection views …