Assessing the potential of NS2B/NS3 protease inhibitors biomarker in curbing dengue virus infections: In silico vs. In vitro approach

H Norshidah, CH Leow, KE Ezleen… - Frontiers in cellular …, 2023 - frontiersin.org
An increase in the occurrence of viral infectious diseases is a global concern for human
health. According to a WHO report, dengue virus (DENV) is one of the most common viral …

A short survey of dengue protease inhibitor development in the past 6 years (2015–2020) with an emphasis on similarities between DENV and SARS-CoV-2 …

S Murtuja, D Shilkar, B Sarkar, BN Sinha… - Bioorganic & Medicinal …, 2021 - Elsevier
Dengue remains a disease of significant concern, responsible for nearly half of all arthropod-
borne disease cases across the globe. Due to the lack of potent and targeted therapeutics …

Targeting the DENV NS2B-NS3 protease with active antiviral phytocompounds: structure-based virtual screening, molecular docking and molecular dynamics …

P Purohit, S Sahoo, M Panda, PS Sahoo… - Journal of Molecular …, 2022 - Springer
Dengue fever has been a global health concern. Mitigation is a challenging problem due to
non-availability of workable treatments. The most difficult objective is to design a perfect anti …

Machine learning and molecular docking prediction of potential inhibitors against dengue virus

G Hanson, J Adams, DIB Kepgang, LS Zondagh… - Frontiers in …, 2024 - frontiersin.org
Introduction Dengue Fever continues to pose a global threat due to the widespread
distribution of its vector mosquitoes, Aedes aegypti and Aedes albopictus. While the WHO …

Evaluation of the inhibitory potency of anti-dengue phytocompounds against DENV-2 NS2B-NS3 protease: virtual screening, ADMET profiling and molecular …

P Purohit, D Barik, S Agasti, M Panda… - Journal of Biomolecular …, 2024 - Taylor & Francis
Dengue fever has been a worldwide concern, with 50–100 million new infections each year
mainly due to five different serotypes of the Dengue virus (DENV). Designing a perfect anti …

Curcumin as a natural potential drug candidate against important zoonotic viruses and prions: A narrative review

S Azarkar, M Abedi, ASO Lavasani… - Phytotherapy …, 2024 - Wiley Online Library
Zoonotic diseases are major public health concerns and undeniable threats to human
health. Among Zoonotic diseases, zoonotic viruses and prions are much more difficult to …

[PDF][PDF] Insight on the in silico study and biological activity assay of chalcone-based 1, 5-benzothiazepines as potential inhibitor for breast cancer MCF7. CMUJ

N Frimayanti, M Yaeghoobi, I Ikhtiarudin, DRW Putri… - Nat. Sci, 2021 - cmuj.cmu.ac.th
In silico study was performed to twelve 1, 5-benzothiazepine chalcone derivatives with the
protein target from the crystallographic structure modeling of the enzyme tyrosine kinase …

6‐Octadecenoic and Oleic Acid in Liquid Smoke Rice Husk Showed COVID‐19 Inhibitor Properties

I Arundina, N Frimayanti, MDC Surboyo… - Advances in …, 2024 - Wiley Online Library
In recent years, liquid smoke rice husk (LSRH) has shown its therapeutic potency to
diabetes, wound healing, stomatitis, and periodontitis. The phenol, 6‐octadecenoic acid …

Investigating Lycotoxin-An1a (An1a), a defense antiviral peptide from Alopecosa nagpag venom as prospective anti-dengue agent against DENV-2 NS2B-NS3 …

P Purohit, D Barik, J Dansana, BR Meher - Computational Biology and …, 2024 - Elsevier
Dengue fever is a global health concern with no effective therapy. Screening synthetic
chemicals, animal-originated compounds, and phytocompounds against Dengue virus …

3-(3,4-Dimethoxyphenyl)-5-(2-fluorophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole

A Zamri, HY Teruna, S Wulansari, N Herfindo… - Molbank, 2019 - mdpi.com
A new analogue of fluorinated pyrazoline (compound 1) has been synthesized via one-pot
three-component reaction in a sealed-vessel reactor, Monowave 50. The structure of …