Essential tremor (ET) is a centrally driven tremor. It is meanwhile well established that it does
not emerge from one single oscillator but an oscillatory network comprising most parts of the …

Objective. Deep brain stimulation (DBS) is an established and valid therapy for a variety of
pathological conditions ranging from motor to cognitive disorders. Still, much of the DBS …

Essential tremor (ET) is a syndrome of tremor in posture and movement, but recent studies
have revealed additional cerebellar motor disturbances, cognitive disturbances, personality …

Background: The pathophysiology underlying essential tremor (ET) still is poorly
understood. Recent research suggests a pivotal role of the cerebellum in tremor genesis …

Background Essential tremor is regarded to be a disease of the central nervous system.
Neuroimaging is a rapidly growing field with potential benefits to both diagnostics and …

Background The degenerative cerebellar ataxias comprise a large and heterogeneous
group of neurological diseases whose hallmark clinical feature is ataxia, and which are …

Structural changes in Purkinje cells have been identified in the essential tremor cerebellum,
although the mechanisms that underlie these changes remain poorly understood. Climbing …

BACKGROUND: Abnormalities in cerebello-thalamo-cortical pathways have been
suggested as a basis for essential tremor (ET). Two voxel-based morphometry (VBM) …

BACKGROUND: Cerebello-thalamo-cortical (CTC) pathways dysfunction is involved in
pathological oscillations causing tremor in essential tremor (ET). Low-frequency (1 Hz) …

Essential tremor is a neurological syndrome of heterogeneous pathology and aetiology that
is characterized by tremor primarily in the upper extremities. This tremor is commonly …