Adolescence is a particularly vulnerable neurodevelopmental period marked by high rates
of engagement with risky alcohol use. This review summarizes the cognitive and neural …

Per occasion, alcohol consumption is higher in adolescents than in adults in both humans
and laboratory animals, with changes in the adolescent brain probably contributing to this …

Background: Emotional dysregulation (ED) is a transdiagnostic construct defined as the
inability to regulate the intensity and quality of emotions (such as, fear, anger, sadness), in …

Sex differences may play a critical role in modulating how chronic or heavy alcohol use
impacts the brain to cause the development of alcohol use disorder (AUD). AUD is a …

Background Adolescence is a critical biological, psychological, and social developmental
stage involving heightened risk for substance use and associated adverse consequences …

Adolescence is an important neurodevelopmental period marked by rapidly escalating rates
of alcohol and drug use. Over the past decade, research has attempted to disentangle pre …

Fragile X syndrome (FXS) is caused by the full mutation (> 200 CGG repeats) in the Fragile
X Mental Retardation 1 (FMR1) gene. It is the most common inherited cause of intellectual …

Abstract Purpose of Review Suicide is a major public health concern and a leading cause of
death in the US. Alcohol and opioid use disorders (AUD/OUD) significantly increase risk for …

Heavy cannabis use has been frequently associated with increased rates of mental illness
and cognitive impairment, particularly amongst adolescent users. However, the …

Adolescence is an important ontogenetic period that is characterized by behaviors such as
enhanced novelty-seeking, impulsivity, and reward preference, which can give rise to an …