[HTML][HTML] Stress, epigenetics, and aging: unraveling the intricate crosstalk
Aging, as a complex process involving multiple cellular and molecular pathways, is known to
be exacerbated by various stresses. Because responses to these stresses, such as oxidative …
be exacerbated by various stresses. Because responses to these stresses, such as oxidative …
Air pollution-induced placental alterations: an interplay of oxidative stress, epigenetics, and the aging phenotype?
Abstract According to the “Developmental Origins of Health and Disease”(DOHaD) concept,
the early-life environment is a critical period for fetal programming. Given the …
the early-life environment is a critical period for fetal programming. Given the …
Regular, intense exercise training as a healthy aging lifestyle strategy: preventing DNA damage, telomere shortening and adverse DNA methylation changes over a …
Exercise training is one of the few therapeutic interventions that improves health span by
delaying the onset of age-related diseases and preventing early death. The length of …
delaying the onset of age-related diseases and preventing early death. The length of …
Premature physiologic aging as a paradigm for understanding increased risk of adverse health across the lifespan of survivors of childhood cancer
KK Ness, JL Kirkland, MM Gramatges… - Journal of Clinical …, 2018 - ascopubs.org
The improvement in survival of childhood cancer observed across the past 50 years has
resulted in a growing acknowledgment that simply extending the lifespan of survivors is not …
resulted in a growing acknowledgment that simply extending the lifespan of survivors is not …
Genetic impacts on DNA methylation help elucidate regulatory genomic processes
Background Pinpointing genetic impacts on DNA methylation can improve our
understanding of pathways that underlie gene regulation and disease risk. Results We …
understanding of pathways that underlie gene regulation and disease risk. Results We …
Early-life social experience affects offspring DNA methylation and later life stress phenotype
Studies in rodents and captive primates suggest that the early-life social environment affects
future phenotype, potentially through alterations to DNA methylation. Little is known of these …
future phenotype, potentially through alterations to DNA methylation. Little is known of these …
Total, insoluble, and soluble dietary fiber intake and insulin resistance and blood pressure in adolescents
Abstract Background/Objectives To evaluate sex and race differences in fiber intakes, which
are understudied in adolescents, and to investigate whether low insoluble and soluble fiber …
are understudied in adolescents, and to investigate whether low insoluble and soluble fiber …
Role of DNA methylation in human age prediction
N Goel, P Karir, VK Garg - Mechanisms of ageing and development, 2017 - Elsevier
DNA methylation (DNAm) is a fundamental biochemical modification which occurs over the
lifespan of an individual and it is a significant component in the aging process. Methylation …
lifespan of an individual and it is a significant component in the aging process. Methylation …
Linking LOXL2 to cardiac interstitial fibrosis
M Erasmus, E Samodien, S Lecour, M Cour… - International Journal of …, 2020 - mdpi.com
Cardiovascular diseases (CVDs) are the leading causes of death worldwide. CVD
pathophysiology is often characterized by increased stiffening of the heart muscle due to …
pathophysiology is often characterized by increased stiffening of the heart muscle due to …
Occupational exposure to pesticides in tobacco fields: the integrated evaluation of nutritional intake and susceptibility on genomic and epigenetic instability
Pesticides used at tobacco fields are associated with genomic instability, which is proposed
to be sensitive to nutritional intake and may also induce epigenetic changes. We evaluated …
to be sensitive to nutritional intake and may also induce epigenetic changes. We evaluated …