Protein lipidation, including cysteine prenylation, N-terminal glycine myristoylation, cysteine
palmitoylation, and serine and lysine fatty acylation, occurs in many proteins in eukaryotic …

Protein palmitoylation, a classical and common lipid modification, regulates diverse aspects
of neuronal protein trafficking and function. The reversible nature of palmitoylation provides …

This review is concerned with the structures and mechanisms of a superfamily of regulatory
GTP hydrolases (G proteins). G proteins include Ras and its close homologs, translation …

In multicellular organisms from Caenorhabditis elegans to Homo sapiens, the maintenance
of homeostasis is dependent on the continual flow and processing of information through a …

• Introduction• Membrane lipid composition• Membrane lipid structure• Membrane lipid
organization‐Why so many different lipids?‐Lipid mixing and demixing‐Lateral pressure …

Palmitoylation is a lipid modification that plays a critical role in protein trafficking and function
throughout the nervous system. Palmitoylation of PSD-95 is essential for its regulation of …

▪ Abstract Protein S-palmitoylation is the thioester linkage of long-chain fatty acids to
cysteine residues in proteins. Addition of palmitate to proteins facilitates their membrane …

The ability of cells to communicate with and respond to their external environment is critical
for their continued existence. A universal feature of this communication is that the external …

Thioacylation is one of a handful of reversible covalent protein modifications, but the
enzymes responsible for addition and removal of long chain fatty acids from protein cysteine …

Heterotrimeric (af3y) G proteins act as molecular switches to relay information from activated
receptors to appropriate effector proteins (eg adenylyl cyclase, phosphatidylinositol-specific …