Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Versatile types of inorganic/organic NIR-IIa/IIb fluorophores: from strategic design toward molecular imaging and theranostics

Y Liu, Y Li, S Koo, Y Sun, Y Liu, X Liu, Y Pan… - Chemical …, 2021 - ACS Publications
In vivo imaging in the second near-infrared window (NIR-II, 1000–1700 nm), which enables
us to look deeply into living subjects, is producing marvelous opportunities for biomedical …

In vivo non-invasive confocal fluorescence imaging beyond 1,700 nm using superconducting nanowire single-photon detectors

F Wang, F Ren, Z Ma, L Qu, R Gourgues, C Xu… - Nature …, 2022 - nature.com
Light scattering by biological tissues sets a limit to the penetration depth of high-resolution
optical microscopy imaging of live mammals in vivo. An effective approach to reduce light …

Design of superior phototheranostic agents guided by Jablonski diagrams

G Feng, GQ Zhang, D Ding - Chemical Society Reviews, 2020 - pubs.rsc.org
Phototheranostics represents a promising direction for modern precision medicine, which
has recently attracted great research interest from multidisciplinary research areas. Organic …

The chemistry of organic contrast agents in the NIR‐II window

J Mu, M Xiao, Y Shi, X Geng, H Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Optical imaging, especially fluorescence and photoacoustic imaging, is a non‐invasive
imaging approach with high spatial and temporal resolution and high sensitivity, compared …

Molecular engineering of NIR‐II fluorophores for improved biomedical detection

Z Lei, F Zhang - Angewandte Chemie International Edition, 2021 - Wiley Online Library
The development of fluorophores for the second near‐infrared window (NIR‐II, 1000–1700
nm) represents an emerging, significant, and vibrant field in analytic chemistry, chemical …

Management of fluorescent organic/inorganic nanohybrids for biomedical applications in the NIR-II region

B Li, M Zhao, J Lin, P Huang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Biomedical fluorescence imaging in the second near-infrared (NIR-II, 100–1700 nm) window
provides great potential for visualizing physiological and pathological processes, owing to …

Acceptor engineering for NIR-II dyes with high photochemical and biomedical performance

A Ji, H Lou, C Qu, W Lu, Y Hao, J Li, Y Wu… - nature …, 2022 - nature.com
It is highly important and challenging to develop donor-acceptor-donor structured small-
molecule second near-infrared window (NIR-II) dyes with excellent properties such as water …

Multimodal imaging‐guided photothermal immunotherapy based on a versatile NIR‐II aggregation‐induced emission luminogen

D Yan, M Wang, Q Wu, N Niu, M Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Synergistic photothermal immunotherapy has captured great attention owing to the mutually
strengthening therapeutic outcomes towards both original tumors and abscopal tumors …

Engineered NIR-II fluorophores with ultralong-distance molecular packing for high-contrast deep lesion identification

Z Feng, Y Li, S Chen, J Li, T Wu, Y Ying… - Nature …, 2023 - nature.com
The limited signal of long-wavelength near-infrared-II (NIR-II, 900–1880 nm) fluorophores
and the strong background caused by the diffused photons make high-contrast fluorescence …