Chronic exposures to low and high concentrations of ibuprofen elicit different gene response patterns in a euryhaline fish

KM Jeffries, SM Brander, MT Britton, NA Fangue… - … Science and Pollution …, 2015 - Springer
Ibuprofen is one of the most commonly detected pharmaceuticals in wastewater effluent;
however, the effects of ibuprofen on aquatic organisms are poorly understood. This study …

[HTML][HTML] Hydroxylated benzo [c] phenanthrene metabolites cause osteoblast apoptosis and skeletal abnormalities in fish

N Suzuki, M Honda, M Sato, S Yoshitake… - Ecotoxicology and …, 2022 - Elsevier
To study the toxicity of 3-hydroxybenzo [c] phenanthrene (3-OHBcP), a metabolite of benzo
[c] phenanthrene (BcP), first we compared it with its parent compound, BcP, using an in ovo …

Combined toxicities of tributyltin and polychlorinated biphenyls on the development and hatching of Japanese medaka (Oryzias latipes) embryos via in ovo …

X Qiu, SG Kim, IJ Kang, T Hano, Y Shimasaki… - Chemosphere, 2019 - Elsevier
Tributyltin (TBT) and polychlorinated biphenyls (PCBs) are typical organic pollutants that co-
exist in the aquatic environment. Despite increasing awareness of their combined impacts …

Detoxification roles of tributyltin-binding protein type 2 in Japanese medaka (Oryzias latipes) exposed to tributyltin

X Qiu, T Takamura, S Enoki, Y Kato-Unoki, Y Takai… - Marine Pollution …, 2020 - Elsevier
Tributyltin-binding protein type 2 (TBT-bp2), a homolog of α1-acid glycoprotein, may
contribute to both accumulation and detoxification of TBT in fish. In this study, we conducted …

Characterization and evolutionary analysis of tributyltin‐binding protein and pufferfish saxitoxin and tetrodotoxin‐binding protein genes in toxic and nontoxic …

Y Hashiguchi, JM Lee, M Shiraishi… - Journal of …, 2015 - academic.oup.com
Understanding the evolutionary mechanisms of toxin accumulation in pufferfishes has been
long‐standing problem in toxicology and evolutionary biology. Pufferfish saxitoxin and …

Soaking RNAi-mediated modification of Sf9 cells for baculovirus expression system by ectopic expression of Caenorhabditis elegans SID-1

J Xu, Y Nagata, H Mon, Z Li, L Zhu, K Iiyama… - Applied microbiology …, 2013 - Springer
RNA interference (RNAi) is a biological phenomenon that silences the expression of genes
of interest. Passive double-stranded RNA (dsRNA) uptake has been uniquely observed in …

RNAi suppression of β-N-acetylglucosaminidase (BmFDL) for complex-type N-linked glycan synthesis in cultured silkworm cells

Y Nagata, JM Lee, H Mon, S Imanishi, SM Hong… - Biotechnology …, 2013 - Springer
Glycoproteins have various biological functions including enzymatic activity, protein stability
and others. Due to the presence of paucimannosidic N-linked glycans, recombinant proteins …

Tributyltin-binding protein type 1 (fish acid glycoprotein) is a potential gatekeeper of ethinylestradiol action in fish

H Hakata, Y Takai, JM Lee, T Kusakabe… - … and Physiology Part C …, 2023 - Elsevier
Tributyltin (TBT)-binding protein type 1 in Japanese medaka (Oryzias latipes)(O. latTBT-bp1)
is a fish lipocalin implicated in TBT binding and detoxification. We purified recombinant O …

Induction of tributyltin-binding protein type 2 in Japanese flounder, Paralichthys olivaceus, by exposure to tributyltin-d27

M Nassef, T Tawaratsumita, Y Oba, H Satone… - Marine pollution …, 2011 - Elsevier
In this study, individual Japanese flounder were intraperitoneally injected with 2μg tributyltin-
d27 (TBT-d27) fish− 1. Blood samples were collected on day 7 after injection. TBT-binding …

Tetrodotoxin-and tributyltin-binding abilities of recombinant pufferfish saxitoxin and tetrodotoxin binding proteins of Takifugu rubripes

H Satone, S Nonaka, JM Lee, Y Shimasaki… - Toxicon, 2017 - Elsevier
We investigated the ability of recombinant pufferfish saxitoxin and tetrodotoxin binding
protein types 1 and 2 of Takifugu rubripes (rTrub. PSTBP1 and rTrub. PSTBP2) to bind to …