Microtubules have fundamental roles in many essential biological processes, including cell
division and intracellular transport. They assemble and disassemble from their two ends …

Microtubules are cytoskeletal filaments central to a wide range of essential cellular functions
in eukaryotic cells. Consequently, cells need to exert tight control over when, where and how …

Background The dynamic properties of microtubules depend on complex nanoscale
structural rearrangements in their end regions. Members of the EB1 and XMAP215 protein …

The microtubule cytoskeleton forms complex macromolecular assemblies with a range of
microtubule-associated proteins (MAPs) that have fundamental roles in cell architecture …

Microtubules are cytoskeletal components involved in pivotal eukaryotic functions such as
cell division, ciliogenesis, and intracellular trafficking. They assemble from αβ-tubulin …

In cells, a complex network of proteins regulates the dynamic growth of microtubules that is
essential for division and migration. In vitro approaches with purified components have so …

Recent studies have found that microtubule-associated proteins (MAPs) can regulate the
dynamical properties of microtubules in unexpected ways. For most MAPs, there is an …

The cytoplasmic dynein-1 (dynein) motor plays a central role in microtubule organisation
and cargo transport. These functions are spatially regulated by association of dynein and its …

The formation and maintenance of microtubules requires their polymerisation, but little is
known about how this polymerisation is regulated in cells. Focussing on the essential …

Cytoplasmic linker-associated proteins (CLASPs) regulate microtubules in fundamental
cellular processes. CLASPs stabilize dynamic microtubules by suppressing microtubule …