Liver cancer is an aggressive disease with a poor outcome. Several hepatic stem/progenitor
markers are useful for isolating a subset of liver cells with stem cell features, known as …

Studies of liver regenerative processes have gained new prominence, generated from
analyses of genetically engineered animal models, the transplantation of human livers, and …

The liver has the unique capacity to regulate its growth and mass. In rodents and humans, it
grows rapidly after resection of more than 50% of its mass. This growth process, as well as …

This study demonstrates that a CD34–, vascular endothelial cadherin–(VE-cadherin–),
AC133+, and fetal liver kinase+ (Flk1+) multipotent adult progenitor cell (MAPC) that …

Livers are comprised of maturational lineages of cells beginning extrahepatically in the
hepato-pancreatic common duct near the duodenum and intrahepatically in zone 1 by the …

Purpose A balanced chromosomal translocation, t (15; 19), resulting in the BRD4-NUT
oncogene, has been identified in a lethal carcinoma of young people, a disease described …

Several studies suggested the presence of stem cells in the adult normal human liver;
however, a population with stem cell properties has not yet been isolated. The purpose of …

Cholangiolocellular carcinoma (CLC), a subtype of cholangiocellular carcinoma (CC), is
thought to originate from the ductules/canals of Hering, where hepatic progenitor cells …

The molecular signals that control the maintenance and activation of liver stem/progenitor
cells are poorly understood, and the role of liver progenitor cells in hepatic tumorigenesis is …

Although the existence of cancer stem cells (CSCs) was first proposed over 40 years ago,
only in the past decade have these cells been identified in hematological malignancies, and …