Microbial fibrinolytic enzymes as anti-thrombotics: production, characterisation and prodigious biopharmaceutical applications
Cardiac disorders such as acute myocardial infarction, embolism and stroke are primarily
attributed to excessive fibrin accumulation in the blood vessels, usually consequential in …
attributed to excessive fibrin accumulation in the blood vessels, usually consequential in …
Purification, physicochemical properties, and statistical optimization of fibrinolytic enzymes especially from fermented foods: a comprehensive review
AMM Ali, SCB Bavisetty - International Journal of Biological …, 2020 - Elsevier
Fibrinolytic enzymes are proteases responsible for cleavage of fibrin mesh in thrombus clots,
which are the primary causative agents in cardiovascular diseases. Developing safe …
which are the primary causative agents in cardiovascular diseases. Developing safe …
Delivery of tissue plasminogen activator and streptokinase magnetic nanoparticles to target vascular diseases
A Tadayon, R Jamshidi, A Esmaeili - International journal of pharmaceutics, 2015 - Elsevier
Thrombolytic therapy for acute myocardial infarction standardly makes use of the
medications streptokinase (SK) and tissue plasminogen activator (tPA). In this study, the …
medications streptokinase (SK) and tissue plasminogen activator (tPA). In this study, the …
Purification, biochemical, and structural characterization of a novel fibrinolytic enzyme from Mucor subtilissimus UCP 1262
Fibrinolytic proteases are enzymes that degrade fibrin. They provide a promising alternative
to existing drugs for thrombolytic therapy. A protease isolated from the filamentous fungus …
to existing drugs for thrombolytic therapy. A protease isolated from the filamentous fungus …
[HTML][HTML] Exploring the in vitro thrombolytic activity of nattokinase from a new strain Pseudomonas aeruginosa CMSS
SD Chandrasekaran, M Vaithilingam… - Jundishapur journal …, 2015 - ncbi.nlm.nih.gov
Background: Thrombolytic therapy has become a conventional treatment for acute
myocardial infarction (AMI), yet currently, clinically prescribed thrombolytic drugs have …
myocardial infarction (AMI), yet currently, clinically prescribed thrombolytic drugs have …
Nattokinase: an updated critical review on challenges and perspectives
E Selvarajan, N Bhatnagar - Cardiovascular & Hematological …, 2017 - ingentaconnect.com
Background: Natto, a fermented soybean food, has been consumed by oriental people for
more than 1000 years. Nattokinase, formerly called subtilisin NAT, is a well-studied protease …
more than 1000 years. Nattokinase, formerly called subtilisin NAT, is a well-studied protease …
Phenotypic and genomic insights into mutant with high nattokinase-producing activity induced by carbon ion beam irradiation of Bacillus subtilis
Y Sheng, S Zhang, X Li, S Wang, T Liu, C Wang… - International Journal of …, 2024 - Elsevier
Nattokinase (NK) is found in fermented foods and has high fibrinolytic activity, which makes
it promising for biological applications. In this study, a mutant strain (Bacillus subtilis ZT-S1 …
it promising for biological applications. In this study, a mutant strain (Bacillus subtilis ZT-S1 …
Improvement of soybean cultivars for natto production through the selection of seed morphological and physiological characteristics and seed compositions: a review
DM Escamilla, ML Rosso, DL Holshouser… - Plant …, 2019 - Wiley Online Library
Natto, a traditional soyfood fermented by Bacillus subtilis (natto), is prepared by
steaming/cooking of soaked soybean seeds followed by inoculation with the bacteria and …
steaming/cooking of soaked soybean seeds followed by inoculation with the bacteria and …
[PDF][PDF] Characterization of a novel fibrinolytic enzyme, BsfA, from Bacillus subtilis ZA400 in Kimchi reveals its pertinence to thrombosis treatment
MJ Ahn, HJ Ku, SH Lee, JH Lee - Journal of Microbiology and …, 2015 - jmb.or.kr
Recently, the cardiovascular disease has been widely problematic in humans probably due
to fibrin formation via the unbalanced Western style diet. Although direct (human plasmin) …
to fibrin formation via the unbalanced Western style diet. Although direct (human plasmin) …
Production, Purification and Stability Studies on Nattokinase: A Therapeutic Protein Extracted from Mutant Pseudomonas aeruginosa CMSS Isolated from Bovine Milk
CS Devi, V Mohanasrinivasan, P Sharma… - International Journal of …, 2016 - Springer
Nattokinase (NK) is a potent fibrinolytic enzyme with the potential for fighting against
cardiovascular diseases. In this study, UV mutated Pseudomonas aeruginosa CMSS was …
cardiovascular diseases. In this study, UV mutated Pseudomonas aeruginosa CMSS was …