[HTML][HTML] Neutrophils: between host defence, immune modulation, and tissue injury

P Kruger, M Saffarzadeh, ANR Weber, N Rieber… - PLoS …, 2015 - journals.plos.org
Neutrophils, the most abundant human immune cells, are rapidly recruited to sites of
infection, where they fulfill their life-saving antimicrobial functions. While traditionally …

[HTML][HTML] Neutrophils: molecules, functions and pathophysiological aspects

V Witko-Sarsat, P Rieu, B Descamps-Latscha… - Laboratory …, 2000 - nature.com
CONCLUSION The notion that inflammation is the net resultant of pro and contra
inflammatory pathways (Fauve, 1980) is well illustrated by the dual role of neutrophils which …

Survival of Staphylococcus aureus inside neutrophils contributes to infection

HD Gresham, JH Lowrance, TE Caver… - The Journal of …, 2000 - journals.aai.org
Neutrophils have long been regarded as essential for host defense against Staphylococcus
aureus infection. However, survival of the pathogen inside various cells, including …

[PDF][PDF] Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150, 95 glycoproteins

DC Anderson, TA Springer - Annual review of medicine, 1987 - timothyspringer.org
Leukocyte adhesion deficiency (LAD) is a recently recognized autosomal recessive trait
characterized by recurrent bacterial infections, impaired pus formation and wound healing …

Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in …

CW Smith, SD Marlin, R Rothlein… - The Journal of …, 1989 - Am Soc Clin Investig
The adherence of human neutrophils to human umbilical vein endothelial cells (HUVEC) is
partially dependent on the CD11/CD18 family of glycoproteins on the neutrophil and ICAM-1 …

Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18

TG Diacovo, SJ Roth, JM Buccola, DF Bainton… - 1996 - ashpublications.org
Platelets bound to thrombogenic surfaces have been shown to support activation-dependent
firm adhesion of neutrophils in flow following selectin-mediated tethering and rolling. The …

How neutrophils kill fungi

RP Gazendam, A van de Geer, D Roos… - Immunological …, 2016 - Wiley Online Library
Neutrophils play a critical role in the prevention of invasive fungal infections. Whereas
mouse studies have demonstrated the role of various neutrophil pathogen recognition …

The severe and moderate phenotypes of heritable Mac-1, LFA-1 deficiency: their quantitative definition and relation to leukocyte dysfunction and clinical features

DC Anderson, FC Schmalsteig… - Journal of Infectious …, 1985 - academic.oup.com
An inherited syndrome characterized by recurrent or progressive necrotic soft-tissue
infections, diminished pus formation, impaired wound healing, granulocytosis, and/or …

The β-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in …

Y Xia, V Vetvicka, J Yan, M Hanikýřová… - The Journal of …, 1999 - journals.aai.org
Abstract Mouse leukocyte CR3 (Mac-1, α M β 2 integrin) was shown to function as a receptor
for β-glucans in the same way as human CR3. Soluble zymosan polysaccharide (SZP) or …

Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins.

C Nathan, S Srimal, C Farber, E Sanchez… - The Journal of cell …, 1989 - rupress.org
Human polymorphonuclear leukocytes (PMN) released large quantities of hydrogen
peroxide in response to tumor necrosis factor, but only when the cells were adherent to …