In this review, we summarize our knowledge about mitochondrial potassium channels, with
a special focus on unanswered questions in this field. The following potassium channels …

Mitochondrial potassium channels are believed to contribute to cytoprotection of injured
cardiac and neuronal tissues. The following potassium channels have been described in the …

Mitochondrial division is critical for the maintenance and regulation of mitochondrial
function, quality and distribution. This process is controlled by cytosolic actin-based …

Oxidative stress and Ca2+ toxicity are mechanisms of hypoxic–ischemic (HI) brain injury.
This work investigates if partial inhibition of mitochondrial respiratory chain protects HI brain …

Several neurodegenerative diseases and brain injury involve reactive oxygen species and
implicate oxidative stress in disease mechanisms. Hydrogen peroxide (H 2 O 2) formation …

Abstract Ca 2+-activated K+ channels (K Ca) are expressed at the plasma membrane and in
cellular organelles. Expression of all K Ca channel subtypes (BK, IK and SK) has been …

Preconditioning represents the condition where transient exposure of cells to an initiating
event leads to protection against subsequent, potentially lethal stimuli. Recent studies have …

Pretreatment of tissues with potassium channel openers (KCO's) has been observed to be
cytoprotective in a broad variety of insults. This phenomenon has been proposed to be …

All cells contain ion channels in their outer (plasma) and inner (organelle) membranes. Ion
channels, similar to other proteins, are targets of oxidative impact, which modulates ion …

In this review, we describe key signaling pathways regulating potassium channels present in
the inner mitochondrial membrane. The signaling cascades covered here include …