Oxidative stress and antioxidant defense in fish: the implications of probiotic, prebiotic, and synbiotics

SH Hoseinifar, S Yousefi, H Van Doan… - Reviews in Fisheries …, 2020 - Taylor & Francis
In fish, like other organisms, the lack of balance between the production of reactive oxygen
species (ROS) and antioxidant defense system (so-called oxidative stress) can cause DNA …

[HTML][HTML] Effects of fluoxetine on fish: What do we know and where should we focus our efforts in the future?

D Correia, I Domingues, M Faria, M Oliveira - Science of the Total …, 2023 - Elsevier
Fluoxetine is one of the most studied and detected selective serotonin reuptake inhibitors in
the aquatic environment, found at concentrations ranging from ng/L to μg/L. Its presence in …

[HTML][HTML] Impact of environmentally relevant concentrations of fluoxetine on zebrafish larvae: from gene to behavior

D Correia, M Bellot, E Prats, C Gómez-Canela, H Moro… - Chemosphere, 2023 - Elsevier
Fluoxetine is widely prescribed for the treatment of depressive states, acting at the level of
the central nervous system, consequently affecting non-target organisms. This study aimed …

Depressed, hypertense and sore: Long-term effects of fluoxetine, propranolol and diclofenac exposure in a top predator fish

IA Duarte, P Reis-Santos, SC Novais, LD Rato… - Science of the total …, 2020 - Elsevier
Pharmaceutical compounds are continuously released into the aquatic environment,
resulting in their ubiquitous presence in many estuarine and coastal systems. As …

Developmental toxicity and biological responses of zebrafish (Danio rerio) exposed to anti-inflammatory drug ketoprofen

B Rangasamy, D Hemalatha, C Shobana, B Nataraj… - Chemosphere, 2018 - Elsevier
Ketoprofen a nonsteroidal anti-inflammatory drug (NSAID) is widely used in over-the-counter
to treat pain, swelling and inflammation. Due to extensive application these drugs has been …

Assessing biological effects of fluoxetine in developing zebrafish embryos using gas chromatography-mass spectrometry based metabolomics

P Mishra, Z Gong, BC Kelly - Chemosphere, 2017 - Elsevier
Continuous low-dose exposure of pharmaceutically active compounds (PhACs) in aquatic
ecosystems is a concern worldwide. In this study, we utilized a gas chromatography mass …

Fluoxetine modulates the transcription of genes involved in serotonin, dopamine and adrenergic signalling in zebrafish embryos

V Cunha, P Rodrigues, MM Santos… - Chemosphere, 2018 - Elsevier
Neurotransmitters pathways in fish and mammals are phylogenetically conserved.
Therefore, the environmental presence of psychopharmaceuticals, such as fluoxetine (FLU) …

Norfluoxetine and venlafaxine in zebrafish larvae: Single and combined toxicity of two pharmaceutical products relevant for risk assessment

P Rodrigues, V Cunha, L Oliva-Teles, M Ferreira… - Journal of Hazardous …, 2020 - Elsevier
Antidepressant metabolites are found in natural and waste waters. However, investigation of
their toxic effects on aquatic animals, single or in mixture with other occurring psychoactive …

Halogen-free organophosphorus flame retardants caused oxidative stress and multixenobiotic resistance in Asian freshwater clams (Corbicula fluminea)

S Yan, H Wu, J Qin, J Zha, Z Wang - Environmental pollution, 2017 - Elsevier
Halogen-free organophosphorus flame retardants are widespread in aquatic environments.
Although it has been documented that they affect the behavior and reproduction of aquatic …

Acute exposure to fluoxetine leads to oxidative stress and hematological disorder in Danio rerio adults

JM Orozco-Hernández, GA Elizalde-Velázquez… - Science of The Total …, 2023 - Elsevier
Fluoxetine (FLX), a selective serotonin reuptake inhibitor (SSRI), is consistently introduced
into the environment due to its ongoing consumption and inadequate removal by …