Myelin fat facts: an overview of lipids and fatty acid metabolism

Y Poitelon, AM Kopec, S Belin - Cells, 2020 - mdpi.com
Myelin is critical for the proper function of the nervous system and one of the most complex
cell–cell interactions of the body. Myelination allows for the rapid conduction of action …

The human fatty acid-binding protein family: evolutionary divergences and functions

RL Smathers, DR Petersen - Human genomics, 2011 - Springer
Fatty acid-binding proteins (FABPs) are members of the intracellular lipid-binding protein
(iLBP) family and are involved in reversibly binding intracellular hydrophobic ligands and …

[HTML][HTML] Exome sequence analysis suggests that genetic burden contributes to phenotypic variability and complex neuropathy

C Gonzaga-Jauregui, T Harel, T Gambin, M Kousi… - Cell reports, 2015 - cell.com
Summary Charcot-Marie-Tooth (CMT) disease is a clinically and genetically heterogeneous
distal symmetric polyneuropathy. Whole-exome sequencing (WES) of 40 individuals from 37 …

Diverse roles of fatty acid binding proteins (FABPs) in development and pathogenesis of cancers

M Amiri, S Yousefnia, FS Forootan, M Peymani… - Gene, 2018 - Elsevier
One of the most importantly involved pathways in cancer development is fatty-acid signaling
pathway. Synthesized lipids as energetic sources are consumed by cancer cells for …

Evolution of genetic and genomic features unique to the human lineage

M O'bleness, VB Searles, A Varki, P Gagneux… - Nature Reviews …, 2012 - nature.com
Given the unprecedented tools that are now available for rapidly comparing genomes, the
identification and study of genetic and genomic changes that are unique to our species have …

Role of fatty acid binding proteins (FABPs) in cancer development and progression

IH McKillop, CA Girardi, KJ Thompson - Cellular signalling, 2019 - Elsevier
Fatty acid binding proteins (FABPs) are small, water soluble proteins that bind long chain
fatty acids and other biologically active ligands to facilitate intracellular localization. Twelve …

The concise guide to PHARMACOLOGY 2013/14: overview

SPH Alexander, HE Benson… - British journal of …, 2013 - Wiley Online Library
Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

PMP2/FABP8 induces PI (4, 5) P2-dependent transbilayer reorganization of sphingomyelin in the plasma membrane

M Abe, A Makino, M Murate, F Hullin-Matsuda… - Cell Reports, 2021 - cell.com
Sphingomyelin (SM) is a mammalian lipid mainly distributed in the outer leaflet of the
plasma membrane (PM). We show that peripheral myelin protein 2 (PMP2), a member of the …

Myelin‐specific proteins: A structurally diverse group of membrane‐interacting molecules

H Han, M Myllykoski, S Ruskamo, C Wang… - Biofactors, 2013 - Wiley Online Library
The myelin sheath is a multilayered membrane in the nervous system, which has unique
biochemical properties. Myelin carries a set of specific high‐abundance proteins, the …

Fatty acid binding protein as a new age biomarker

H Shand, S Patra, S Ghorai - Clinica Chimica Acta, 2024 - Elsevier
Small lipid-binding proteins known as fatty acid-binding proteins (FABPs) are extensively
expressed in cells having elevated levels of fatty acid (FA) metabolism. There are ten known …