The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets
Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …
originating from different cell compartments. EVs participate in many essential physiological …
The role of miRNAs in male human reproduction: A systematic review
Background The presence of miRNAs in human reproductive tissue is intriguing and
suggests the possibility that these important regulatory molecules play a role in reproductive …
suggests the possibility that these important regulatory molecules play a role in reproductive …
Exosomal microRNAs in seminal plasma are markers of the origin of azoospermia and can predict the presence of sperm in testicular tissue
Abstract STUDY QUESTION Are exosomal microRNAs (miRNAs) in seminal plasma (SP)
useful as markers of the origin of azoospermia and the presence of sperm in the testis …
useful as markers of the origin of azoospermia and the presence of sperm in the testis …
Systems biology approaches to investigating the roles of extracellular vesicles in human diseases
Extracellular vesicles (EVs) are membrane-enclosed structures secreted by cells. In the past
decade, EVs have attracted substantial attention as carriers of complex intercellular …
decade, EVs have attracted substantial attention as carriers of complex intercellular …
Using miRNAs as diagnostic biomarkers for male infertility: Opportunities and challenges
A Vashisht, GK Gahlay - Molecular Human Reproduction, 2020 - academic.oup.com
The non-coding genome has been extensively studied for its role in human development
and diseases. MicroRNAs (miRNAs) are small non-coding RNAs, which can regulate the …
and diseases. MicroRNAs (miRNAs) are small non-coding RNAs, which can regulate the …
Human sperm RNA in male infertility
R Cannarella, A Crafa, R Curto, LM Mongioì… - Nature Reviews …, 2024 - nature.com
The function and value of specific sperm RNAs in apparently idiopathic male infertility are
currently poorly understood. Whether differences exist in the sperm RNA profile between …
currently poorly understood. Whether differences exist in the sperm RNA profile between …
Microfluidics facilitating the use of small extracellular vesicles in innovative approaches to male infertility
Sperm are transcriptionally and translationally quiescent and, therefore, rely on the seminal
plasma microenvironment for function, survival and fertilization of the oocyte in the oviduct …
plasma microenvironment for function, survival and fertilization of the oocyte in the oviduct …
A panel of extracellular vesicle long noncoding RNAs in seminal plasma for predicting testicular spermatozoa in nonobstructive azoospermia patients
Y Xie, J Yao, X Zhang, J Chen, Y Gao… - Human …, 2020 - academic.oup.com
STUDY QUESTION Whether the testis-specific extracellular vesicle (EV) long noncoding
RNAs (lncRNAs) in seminal plasma could be utilized to predict the presence of testicular …
RNAs (lncRNAs) in seminal plasma could be utilized to predict the presence of testicular …
MicroRNAs in spermatogenesis dysfunction and male infertility: clinical phenotypes, mechanisms and potential diagnostic biomarkers
Z Shi, M Yu, T Guo, Y Sui, Z Tian, X Ni… - Frontiers in …, 2024 - frontiersin.org
Infertility affects approximately 10–15% of couples worldwide who are attempting to
conceive, with male infertility accounting for 50% of infertility cases. Male infertility is related …
conceive, with male infertility accounting for 50% of infertility cases. Male infertility is related …
Altered non‐coding RNA profiles of seminal plasma extracellular vesicles of men with poor semen quality undergoing in vitro fertilization treatment
Background Currently, the precise mechanisms that underline male infertility are still
unclear. Accumulating data implicate non‐coding RNA cargo of seminal plasma …
unclear. Accumulating data implicate non‐coding RNA cargo of seminal plasma …