Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

There is a great clinical need to identify the underlying mechanisms, as well as related
biomarkers, and treatment targets, for traumatic brain injury (TBI). Neuroinflammation is a …

Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Alzheimer's disease (AD) is a neurodegenerative disease that causes late-onset dementia.
The R47H variant of the microglial receptor TREM2 triples AD risk in genome-wide …

Introduction Management of traumatic brain injury (TBI) includes invasive monitoring to
prevent secondary brain injuries. Intracranial pressure (ICP) monitor is the main …

Traumatic cerebral vascular injury (TCVI) is a very frequent, if not universal, feature after
traumatic brain injury (TBI). It is likely responsible, at least in part, for functional deficits and …

This review recounts the definitions and research evidence supporting the multifaceted roles
of neuroinflammation in the injured brain following trauma. We summarise the literature …

Coma and disordered consciousness are common manifestations of acute neurological
conditions and are among the most pervasive and challenging aspects of treatment in …

Traumatic brain injury (TBI) is a complex and heterogeneous disorder with a tremendous
public health burden. It is grossly defined as an alteration in brain function or other evidence …

Cortical spreading depolarization (CSD) is a promising target for neuroprotective therapy in
traumatic brain injury (TBI). We explored the effect of NMDA receptor antagonism on …