In this FlyBook chapter, we present a survey of the current literature on the development of
the hematopoietic system in Drosophila. The Drosophila blood system consists entirely of …

In the animal kingdom, innate immunity is the first line of defense against invading
pathogens. The dangers of microbial and parasitic attacks are countered by similar …

Immune cells provide defense against non‐self and have recently been shown to also play
key roles in diverse processes such as development, metabolism, and tumor progression …

Cellular immune responses require the generation and recruitment of diverse blood cell
types that recognize and kill pathogens. In Drosophila melanogaster larvae, immune …

Drosophila has been extensively used to model the human blood-immune system, as both
systems share many developmental and immune response mechanisms. However, while …

Much of our knowledge on hematopoiesis, hematopoietic compartments, hematopoietic cell
lineages and immunity has been derived from studies on the vertebrate immune system. The …

Analyses of the Drosophila hematopoietic system are becoming more and more prevalent
as developmental and functional parallels with vertebrate blood cells become more evident …

The catalog of the Drosophila immune cells was until recently limited to three major cell
types, based on morphology, function and few molecular markers. Three recent single cell …

Phagocytosis is an ancient mechanism central to both tissue homeostasis and immune
defense. Both the identity of the receptors that mediate bacterial phagocytosis and the …

Within the hemolymph, insect hemocytes constitute a heterogeneous population of
macrophage-like cells that play important roles in innate immunity, homeostasis and …