Effects of coenzyme Q10 on statin‐induced myopathy: an updated meta‐analysis of randomized controlled trials

H Qu, M Guo, H Chai, W Wang, Z Gao… - Journal of the American …, 2018 - Am Heart Assoc
Background Previous studies have demonstrated a possible association between the
induction of coenzyme Q10 (CoQ10) after statin treatment and statin‐induced myopathy …

Simvastatin effects on inflammation and platelet activation markers in hypercholesterolemia

C Barale, C Frascaroli, R Senkeev… - BioMed Research …, 2018 - Wiley Online Library
Background. Beside the lipid‐lowering effect, statins slow the progression of atherosclerosis
by exerting anti‐inflammatory and platelet inhibiting effects. We investigated whether platelet …

[PDF][PDF] Pharmacological aspects of statins are relevant to their structural and physicochemical properties

Z Althanoon, IM Faisal, AA Ahmad… - Systematic Reviews in …, 2020 - academia.edu
Statins are group of hypolipidemic agents that are effective at lowering blood lipid levels
subsequently improving ischemia associated pathology of atherosclerosis. This beneficial …

[PDF][PDF] Effects of Hypericum perforatum on serum lipid vascular systems in mice

ZS Hamed, RR Abed, MS Almashhadany… - Iraqi Journal of …, 2022 - iasj.net
Herbal products are increasingly used against lipid to attenuate its negative impact on
vasculature system. However, there are uncertainty regarding the best administration …

Fluvoxamine Provide a Gastro-Protection Against Vitiated Insult.

SW Abdulqader, IM Faisal, MG Saeed… - Indian Journal of …, 2022 - search.ebscohost.com
The etiology of peptic ulcer disease is multifactorial and remains an enigma over the last
decades. The central parameter is the acid secretion; whose control is under the …

A critical role for cystathionine-β-synthase in hydrogen sulfide-mediated hypoxic relaxation of the coronary artery

J Donovan, PS Wong, RE Roberts, MJ Garle… - Vascular …, 2017 - Elsevier
Hypoxia-induced coronary artery vasodilatation protects the heart by increasing blood flow
under ischemic conditions, however its mechanism is not fully elucidated. Hydrogen sulfide …

Simvastatin Inhibits L-Type Ca2+-Channel Activity Through Impairment of Mitochondrial Function

L Curry, H Almukhtar, J Alahmed… - Toxicological …, 2019 - academic.oup.com
Plasma membrane ion channels and mitochondrial electron transport complexes (mETC)
are recognized “off targets” for certain drugs. Simvastatin is one such drug, a lipophilic statin …

[PDF][PDF] MIRABEGRON INDUCED RELAXATION OF ISOLATED BOVINE CORONARY SEGMENTS: ROLE OF NO AND K+ CHANNEL.

R Almallah, H Almukhtar - Georgian Medical News, 2024 - researchgate.net
Background: It was already known that mirabegron, a β3-adrenoceptor agonist, affected
cardiac muscle, data also demonstrated that mirabegron induced a relaxant effect in rat …

[PDF][PDF] Iraqi Journal of Pharmacy

EA Alhafith, HM Almukhtar… - Iraqi Journal of …, 2024 - researchgate.net
Iraqi Journal of Pharmacy Page 1 Iraqi Journal of Pharmacy 21(4) (2024) 155-116 Research
Article: Nebivolol, but not Propranolol, Induced Relaxation of the Isolated Bovine Coronary …

Effect of mitochondrial complex III inhibitors on the regulation of vascular tone in porcine coronary artery

M Saarti, H Almukhtar, PA Smith, RE Roberts - European Journal of …, 2021 - Elsevier
In order to gain insight into the regulation of vascular tone by mitochondria, the effects of
mitochondrial complex III inhibitors on contractile responses in porcine isolated coronary …