Clinical translation of nanomedicine

Y Min, JM Caster, MJ Eblan, AZ Wang - Chemical reviews, 2015 - ACS Publications
Clinical Translation of Nanomedicine | Chemical Reviews ACS ACS Publications C&EN CAS
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Tumor angiogenesis and anti‑angiogenic gene therapy for cancer

T Li, G Kang, T Wang, HE Huang - Oncology letters, 2018 - spandidos-publications.com
When Folkman first suggested a theory about the association between angiogenesis and
tumor growth in 1971, the hypothesis of targeting angiogenesis to treat cancer was formed …

Nanoparticle-mediated targeted drug delivery for breast cancer treatment

PY Liyanage, SD Hettiarachchi, Y Zhou, A Ouhtit… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Breast cancer (BC) is the most common malignancy in women worldwide, and one of the
deadliest after lung cancer. Currently, standard methods for cancer therapy including BC are …

Nonviral vectors for gene delivery

MA Mintzer, EE Simanek - Chemical reviews, 2009 - ACS Publications
Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

Drug delivery strategies for platinum-based chemotherapy

RJ Browning, PJT Reardon, M Parhizkar, RB Pedley… - ACS …, 2017 - ACS Publications
Few chemotherapeutics have had such an impact on cancer management as cis-
diamminedichloridoplatinum (II)(CDDP), also known as cisplatin. The first member of the …

Nanoparticles-based drug delivery and gene therapy for breast cancer: Recent advancements and future challenges

Z Mirza, S Karim - Seminars in cancer biology, 2021 - Elsevier
Breast cancer (BC) is amongst the most lethal cancer among females and conventional
treatment methods like surgery, radiotherapy and chemotherapy are not effective enough as …

Ovarian cancer: strategies for overcoming resistance to chemotherapy

R Agarwal, SB Kaye - Nature Reviews Cancer, 2003 - nature.com
Ovarian cancer is responsible for 4% of deaths from cancer in women. Treatment comprises
a combination of surgery and chemotherapy, but patients typically experience disease …

Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer

R Nahta, D Yu, MC Hung, GN Hortobagyi… - Nature clinical practice …, 2006 - nature.com
Trastuzumab is a monoclonal antibody targeted against the human epidermal growth factor
receptor (HER) 2 tyrosine kinase receptor, which is overexpressed in approximately 25% of …

Cationic nanocarriers induce cell necrosis through impairment of Na+/K+-ATPase and cause subsequent inflammatory response

X Wei, B Shao, Z He, T Ye, M Luo, Y Sang, X Liang… - Cell research, 2015 - nature.com
Nanocarriers with positive surface charges are known for their toxicity which has limited their
clinical applications. The mechanism underlying their toxicity, such as the induction of …

Emerging use of nanoparticles in diagnosis and treatment of breast cancer

MV Yezhelyev, X Gao, Y Xing, A Al-Hajj, S Nie… - The lancet …, 2006 - thelancet.com
The biological application of nanoparticles is a rapidly developing area of nanotechnology
that raises new possibilities in the diagnosis and treatment of human cancers. In cancer …