Application of molecular docking in elaborating molecular mechanisms and interactions of supramolecular cyclodextrin

T Li, R Guo, Q Zong, G Ling - Carbohydrate polymers, 2022 - Elsevier
The cyclodextrin (CD)-based supramolecular nanomedicines have attracted growing
interest because of their superior characteristics, including desirable biocompatibility, low …

Improved prediction and characterization of anticancer activities of peptides using a novel flexible scoring card method

P Charoenkwan, W Chiangjong, VS Lee… - Scientific reports, 2021 - nature.com
As anticancer peptides (ACPs) have attracted great interest for cancer treatment, several
approaches based on machine learning have been proposed for ACP identification …

Current Perspectives in Detection of Bioactive Compounds From Costus spicatus Through GC–MS and LC‐MS/MS: Antioxidant Properties and In Silico Analysis for …

D Manimaran, A Tessema, MG Yadav… - Biochemistry …, 2025 - Wiley Online Library
Members of the Costus genus are the conventional medicinal plants used in the therapeutic
management of numerous ailments, especially for their antioxidant and pharmacological …

In vitro vascular-protective effects of a tilapia by-product oligopeptide on angiotensin II-induced hypertensive endothelial injury in HUVEC by Nrf2/NF-κB pathways

J Chen, F Gong, MF Chen, C Li, P Hong, S Sun… - Marine drugs, 2019 - mdpi.com
Angiotensin II (Ang II) is closely involved in endothelial injury during the development of
hypertension. In this study, the protective effects of the tilapia by-product oligopeptide Leu …

Recent progress in functional peptides designed for tumor-targeted imaging and therapy

XY Wang, YH Wang, Z Song, XY Hu, JP Wei… - Journal of Materials …, 2021 - pubs.rsc.org
The diagnosis and therapy of tumors are challenging problems in the medical field. Peptides
are derived from living organisms with excellent biocompatibility, low-toxicity/non-toxicity …

Anti-Microbial Activities of Mussel-Derived Recombinant Proteins against Gram-Negative Bacteria

DY Kim, YB Oh, JS Park, YH Min, MC Park - Antibiotics, 2024 - mdpi.com
Many anti-microbial peptides (AMPs) and pro-apoptotic peptides are considered as novel
anti-microbial agents, distinguished by their different characteristics. Nevertheless, AMPs …

A Novel Peptide HIF9-Nano Complex Targeting Apoptosis in Breast Cancer Cells via Modulating HIF Alpha Signaling Cascades

D Manimaran, V Palanisamy, K Rangasamy… - International Journal of …, 2025 - Springer
Background In cancer therapy, cell proliferation can activate apoptotic machinery in the cell
to suppress tumor growth. Though, the number of malignant cells does not effectively …

Anti-Tumorgenic Impact of Nano-Formulated Peptide HIF-Alpha Therapy by DMBA Induced Mammary Carcinoma in Rodent Type

D Manimaran, N Elangovan… - Jordan Journal of …, 2024 - jjournals.ju.edu.jo
Over the past decade, personalized medicine has acquired considerable attention,
emerging as a promising avenue for enhancing cancer treatment and therapy. Within this …

Recent advances in the application of molecular simulation in research on cyclodextrin inclusion.

J Huang, T Li, H Yu, C Chen, H Yuan, H Tian - 2024 - cabidigitallibrary.org
Cyclodextrin (CD) can form inclusion complexes with the guest molecule through
supramolecular interaction, preserving or even enhancing the properties of the guest …